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Biomedical subjects

S R Mravian

Publications and source records attributed to S R Mravian.

At least 37 records · Page 2Linked to original sources
PubMed1998

[Ventricular late potentials and ventricular arrhythmias in noncoronarogenic myocardial diseases].

Hemodynamic parameters and survival were studied in 48 patients with noncoronarogenic myocardial diseases (NCMD). The examination included high-resolution electrocardiography and Holter monitoring of cardiac rhythm. Deterioration of pump capacity of the heart was associated with high-grade arrhythmias (4B and higher) while ventricular late potentials were more characteristic for patients with severe hemodynamic disorders and, in particular, with dilated cardiomyopathy. The prognosis in NCMD is based on clinical evidence on functional class of the heart failure, parameters of central and intrapulmonary hemodynamics.

Adolescent↗
PubMed1994

[Hemodynamics and anaerobic glycolysis during the head-down tilt test in myocarditis patients].

The analysis is presented of the changes observed in hemodynamics and anaerobic metabolism in myocarditis patients given increasing preload. It is shown that the antiorthostatic test can specify substantial deposition of blood in the lesser or greater circulation. Patients with congestive cardiac insufficiency demonstrate more frequently increased lactate levels in the blood of the coronary sinus and reduced myocardial extraction of lactate.

Adolescent↗
PubMed1993

[Disorders of the central and intrapulmonary hemodynamics as an index of the degree of severity in myocarditis patients].

Central and intrapulmonary hemodynamic parameters were examined by direct and indirect methods in 46 patients with myocarditis (25 females and 21 males), which revealed diminished myocardial contractility, which was followed by a regular and significant pulmonary blood pressure and a reduction in the elastic properties of the pulmonary-arteriolar bed. Central and intrapulmonary hemodynamic changes are mostly associated with the development of hypodynamia and more rarely with that of the phase hemodynamic syndrome and more rarely with the volume overloading syndrome.

Adolescent↗
PubMed1991

[Study of myocardial morphology in chronic obstructive bronchitis complicated by pulmonary hypertension based on the results of endomyocardial biopsy].

Endomyocardial biopsy along with right heart catheterization was first performed in 12 patients with chronic obstructive bronchitis complicated by transient or sustained pulmonary hypertension. Light and electron microscopic findings showed signs of severe myocardial dystrophy in 7 patients and prevalent hypertrophy in the remaining patients. Endomyocardial biopsy provided valuable information on the state of the myocardium, yielding evidence for the heretogeneous nature of right ventricular myocardial changes. Two morphological variants of cor pulmonale--hypertrophic and dystrophic--could be identified with regard to the findings.

Biopsy↗
PubMed1991

[Myocardium in chronic obstructive lung diseases].

The analysis of endomyocardial biopsies (10 specimens) and clinical observations suggests the conclusion: myocardial lesions in OPD patients with pulmonary hypertension are due to metabolic and hemodynamic disturbances. In addition to myocardial hypertrophy, myocardial dystrophy contributes to development of cor pulmonale.

Biopsy↗
PubMed1991

[Cardiogenic shock in dilated cardiomyopathy].

The present communication is based on an examination of 33 cases with dilated cardiomyopathy and 48 with severe myocarditis. Nine patients with dilated cardiomyopathy were diagnosed as having developed cardiogenic shock. Clinical examination, echocardiography, right heart and pulmonary artery probing were performed. Cardiogenic shock in dilated cardiomyopathy was demonstrated to be characterized by a progressive decrease in cardiac contractility, no increase in peripheral vascular resistance, and high pulmonary hypertension. Profound cardiomyocyte alterations followed by increased fibrosis of intermuscular and perivascular spaces contribute to the development of cardiogenic shock in dilated cardiomyopathy.

Adult↗
PubMed1991

[Pulmonary hypertension and myocardial contractility in myocarditis].

Hemodynamic studies by direct and indirect methods in patients with myocarditis have revealed that as pulmonary hypertension developed, right-ventricular myocardial contractility and pulmonary arteriolar bed elasticity were decreasing. High pulmonary hypertension and structural shifts in pulmonary artery wall reduced the volumic potentialities of the lesser circulation. The antiorthostatic test was found an important test for the detection of compensatory deposition potentialities of the lesser circulation vessels in myocarditis patients.

Adolescent↗
PubMed1989

[Correlation analysis of hemodynamic and morphological parameters in patients with myocarditis].

Central and intrapulmonary hemodynamic parameters were examined in 40 patients with myocarditis. Morphological evidence for endomyocardial biopsy specimens and morphometric findings were also analyzed. Deterioration of myocardial diastolic relaxation was found to closely correlate with the magnitude of cardiosclerotic changes and cardiomyocytic myolysis. A correlation was also established between the morphometric characteristics of the microcirculatory bed and the parameters of myocardial contractility. Functionally deficiently cardiomyocytic hypertrophy was more profound in severe heart failure.

Adolescent↗