Biomedical subjects
S Rainer
Publications and source records attributed to S Rainer.
Histological picture of the gonads in testicular feminization.
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Luteal phase endometrial cytosol and nuclear progesterone receptors in infertile women.
Progesterone receptor (PR) concentrations in cell nuclei (PRn), in cytosols (PRc) and a percentage of PRn, plasma progesterone level (P) and histological endometrium dating in the secretory phase of the menstrual cycle were studied in three groups of patients. In the control group (group "A"-17 patients) there were infertile patients with normal levels of plasma P and histological dating of the endometrium corresponding to the actual day of the menstrual cycle. In group "B" (7 patients) there were infertile patients with normal plasma P levels and delayed histological finding of the endometrium for 2 or more days (mean 3.3 days)--"pseudocorpus luteum insufficiency". In group "C" there were 3 patients with delayed secretory transformation of the endometrium and low plasma P level (luteal phase defect). In group "B" there was lower concentration of the total PR (for 305.5 fmol/mg DNA), PRc (for 536.8 fmol/mg DNA), higher concentration of PRn (for 233.4 fmol/mg DNA) and for 20.5% higher percentage of PRn, but these values are not significantly different from those in the control group. In group "C" there were higher concentrations of the total PR and percentage of PRn but the sample was too small to permit statistical comparison. On the basis of these results we cannot conclude if in "pseudocorpus luteum insufficiency" a decreased sensitivity of the endometrium is due to the P, or is functional in nature. It will be necessary to continue our work on a larger number of patients and also to study changes in PR concentrations in the follicular phase of the menstrual cycle.
[Transfusion of blood, blood derivatives and plasma substitutes in gynecology and obstetrics].
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[Isosensitization in pregnancy].
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[Therapeutic abortion by uterine aspiration].
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[Simultaneous interstitial and intrauterine pregnancy: successful completion of the intrauterine pregnancy].
The authors describe an extremely rare combination of simultaneous intrauterine and interstitial pregnancy. In spite of the rupture of interstitial pregnancy in the 13th week and cornual resection, it was possible to restrain the intrauterine pregnancy under careful control until the 38th week, when a healthy mature baby was delivered by elective Caesarian section. The cicatrix of the uterus after cornual resection held the pregnancy well. Severe anaemia as a consequence of the bleeding before and during operation was quickly corrected and did not harm the further development of the child.
[Genetics, the law and pregnancy].
Paraphrasing the recent Milunsky's commentary, authors emphasise the doctor's duty and the role in preventing the birth of abnormal children.
[Role of team work in preventing the birth of abnormal children].
In diagnosing and preventing the birth of abnormal children the authors stress the necessity of team work of different specialists and their centralisation at the University complex or hospitals. The results of such a team work organised at the Division of Medical Genetics, Department of Gynecology and Obstetrics in Ljubljana and their experience in detecting some of monogenic, chromosome, and etiologically unknown disorders are presented, as well as the results of the follow-up of certain cases. The value of team work in genetic counselling is also pointed out.
[Pathohistological criteria in the treatment of stage I a cervical carcinoma (author's transl)].
The work is an attempt to define the stage Ia of squamous carcinoma of the cervix on the basis of morphological criteria. These criteria, with the collaboration of pathologist and gynecologist, would allow the best treatment. They are based on the evaluation of the cellular type, mitotic activity, the pattern of invasion, the tissue defense reaction, the presence of lymphatic and vascular spread, and the size of carcinomatous tissue.
[Atypical hyperplasia and endometrial carcinoma (author's transl)].
Data on 167 cases of atypical hyperplasia of the endometrium and 292 cases of adenocarcinoma of the endometrium from 1966 to 1977 are presented. In 41 cases of atypical hyperplasia (24.5%) also adenocarcinoma of the endometrium coexisted. The age distribution revealed that atypical hyperplasia was much frequent in the age group from 40--59, and adenocarcinoma of the endometrium from 59--69. Out of 61 cases of theca- and granulosa-cell tumors of the ovary, 13 cases (21.3%) related to atypical hyperplasia or adenocarcinoma of the endometrium. Out of 27 cases of the Stein-Leventhal syndrome, 3 cases were atypical hyperplasia, one case adenocarcinoma of the endometrium. The data presented suggest that atypical hyperplasia might be a stage in the development of endometrial carcinoma.
[Diagnosis of early forms of cervix carcinoma].
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