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Biomedical subjects

S Rakoff

Publications and source records attributed to S Rakoff.

8 recordsLinked to original sources
PubMed1987

Sjögren's syndrome: severe upper airways obstruction due to primary malignant tracheal lymphoma developing during successful treatment of lymphocytic interstitial pneumonitis.

A wide spectrum of respiratory tract involvement may be seen in Sjögren's syndrome, however, multiple manifestations in one patient are unusual. A 65-year-old woman with a 5-year history of Sjögren's syndrome presented with hoarseness and pulmonary infiltrates. Lymphocytic interstitial pneumonitis, tracheobronchitis with subglottic edema and obstructive small airways disease were initially documented. Dramatic radiographic improvement of the lymphocytic interstitial pneumonitis occurred during 14 months of corticosteroid therapy. However, a rare primary malignant lymphoma of the trachea developed and presented with steroid refractory, upper airways obstruction. Subsequent patient management and the dichotomous behavior of the lymphoid infiltrates are discussed.

Aged↗
PubMed1978

Fibro-optic study of pharyngeal airway during sleep in patients with hypersomnia obstructive sleep-apnea syndrome.

Pharyngeal airway during sleep was observed with help of Fibro-optic flexible bronchoscope and cineradiography in 10 adult patients with Hypersomnia Sleep-Apnea (HSA) syndrome. The results of the study suggest that the structures involved in production of airway obstruction in the patients with HSA syndrome are the muscles of velopharyngeal sphincter and tongue. The laryngeal airway was not obstructed during the episodes of apnea.

Adult↗
PubMed1975

Patterns of velopharyngeal closure in subjects with repaired cleft palate and normal speech: a multi-view videofluoroscopic analysis.

Thirty subjects with repaired palatal clefts and normal speech ranging in age from 2 to 12 years were examined in multiple videofluoroscopic projections in order to assess velopharyngeal closure in three dimensions. The following points became evident from the results of this study: 1. All 30 subjects exhibited contact between the superior border of the velum and the adenoid mass in the nasopharynx. Often, a sharp levator eminance was not formed due to the small space between the velum at rest and the adenoids. Thus, there was little room for the velum to elevate. 2. All 30 subjects showed good localized medial movement of the LAPW at the approximate plane of the hard palate. 3. 10 out of 30 subjects, 33%, had a Passavant's Ridge during speech. All 10 of these subjects utilized the ridge as a point of closure, as well as the adenoids. 4. The observed patterns of closure were consistent across varied consonant utterances. 5. The mechanism of velopharyngel closure in this group of subjects is essentially the same as for normal adult speakers and differs only anatomically due to a lack of verticle head growth in children. Thus, in spite of the presence of adenoids and the lack of verticle head development, the basic sphincteric mechanism of velopharyngeal colsure is utilized in these subjects.

Adenoids↗