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Biomedical subjects

S Rewerk

Publications and source records attributed to S Rewerk.

5 recordsLinked to original sources

Morphological features of enlarged parathyroid glands in B-mode-ultrasound.

Successful preoperative localisation of parathyroid glands is essential for minimal-invasive surgery of hyperparathyroidism. The knowledge of the sonomorphology of the parathyroid glands, therefore, is an important prerequisite. This article shows that the sonomorphology of normal and pathologically transformed parathyroid glands is subject to a wide variety. The often simplified standard description of parathyroid glands as hypoechogenic and oval may lead to false negative cervical ultrasound examinations.

Diagnosis, Differential↗

Local application of hyperthermia in the esophagus with a heatable malleable thermoplastic stent.

OBJECTIVE: This study measures the effect of hyperthermia applied through a heatable stent in the esophagus in order to investigate whether this procedure offers a therapeutic option for tumor treatment. MATERIAL AND METHODS: Thermoplastic malleable stents, with the capacity to be heated after implantation, were placed endoscopically in the middle third of the esophagi of 30 pigs. After placement the stents were heated in vivo for 60 min at temperatures ranging from 43 to 52 degrees C. Temperature was measured in the surrounding tissue at various distances from the stent, determining heat penetration. The esophagi were histologically examined after 7 days. RESULTS: The maximal heating temperature tolerated in the esophagi without transmural necrosis was 46.5 degrees C, when applied twice for 60 min with a pause of 48 h. With this procedure a tumor damaging temperature of 42.5 degrees C was achieved at a maximum distance of 12 mm surrounding the stent. CONCLUSION: Application of hyperthermia through a heatable stent in the esophagus is feasible. The maximal depth of therapeutic temperature achieved by this procedure (12 mm) is not sufficient to heal esophageal cancer, but may be of palliative value.

Animals↗

[Sonographic localisation procedures in hyperparathyroidism -- persistent hyperparathyroidism after removal of four parathyroid glands].

This case report will give an example for the necessity of performing an ultrasound examination of the neck before resection of the parathyroid glands. In end-stage renal failure a 38-year-old man developed secondary hyperparathyroidism (HPT). Four glands were removed. Two years later the patient revealed persisting HPT. At this point an ultrasound examination was performed and demonstrated a fifth parathyroid gland located inside the thyroid gland. The case illustrates the benefit of cervical ultrasound, even in cases of secondary hyperparathyroidism, prior to any cervical exploration.

Adult↗

[Twist-guided thread control: a technique for faster and atraumatic continuous sutures].

A simple technique by twisting the thread in clockwise or counter clockwise direction before tightening the suture can help to produce a regular vascular suture line. In a blinded experiment with 60 vascular anastomosis it was proved that the time needed for suture can be reduced by 15%, and that traumatic touch with surgical instruments can be diminished by 63%.

Anastomosis, Surgical↗

Biodegradation of absorbable sutures in body fluids and pH buffers.

OBJECTIVE: This study measures the influence of body fluids on the loss of tensile strength of absorbable sutures in vitro. METHODS: Nine synthetic absorbable sutures were incubated in different gastrointestinal fluids, as well as in blood and three buffers. Stretch tests were performed after days 0, 7, 14, and 21. RESULTS: Tensile strength varied from 18.5 to 32.8 N, and elasticity varied from 9.5 to 51% of the initial length. The influence of pH, blood, and gastric juice was negligible on all sutures except PDS II. Except for Monocryl, all sutures, especially Polysorb and Vicryl, lost tensile strength much faster in bile, jejunal and pancreatic juices than in the corresponding buffers. CONCLUSION: The biodegradation of sutures varies greatly in different body fluids independent of differences in pH.

Absorbable Implants↗