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S Rodríguez Muñoz

Publications and source records attributed to S Rodríguez Muñoz.

16 recordsLinked to original sources
PubMed2006

Endoscopist controlled administration of propofol: an effective and safe method of sedation in endoscopic procedures.

OBJECTIVES: Propofol is a short-acting, hypnotic agent that is increasingly being used for gastrointestinal endoscopic sedation. There are concerns about the use of propofol by non anesthesiologists due to its potential for respiratory and cardiovascular depression. This report describes our experience concerning effectiveness and safety of propofol administered in endoscopic procedures by the endoscopist and the assistant nurse. METHODS: In this prospective study, a total of 102 consecutive endoscopies (60 colonoscopies and 42 upper endoscopies) performed under sedation with propofol were included. In 27 (26.47%) endoscopies propofol was administered alone and in 75 endoscopies (73.53%) it was combined with benzodiazepines and/or opioids. Seventy-six (74.51%) endoscopies were performed in patients under 65 years of age and 26 (25.49%) in patients over 65 years of age. Ninety-one (89.22%) endoscopies were performed in patients with low surgical risk (ASA I-II) and 11 (10.78%) in patients with high surgical risk. The medication was administered by the endoscopist that performed the procedure and the assistant nurse. RESULTS: The mean dose of propofol used was 72.14 mg for gastroscopies and 71.33 for colonoscopies (p = 0.92). The mean dose of propofol when infused alone was 84.81 mg whereas in combination with benzodiazepines/opioids was 66.93 mg (p = 0.06). The doses of propofol required were lower for those colonoscopies in which midazolam and/or meperidine was combined and in patients over 65 years of age (p = 0.006 y p = 0.001, respectively). Eleven (10.8%) minor complications were reported, and managed by the own endoscopist. Patients had no memories of the procedure. The tolerance rated by the endoscopist was excellent-good, fair, bad-very bad in 83, 5 and 12% of the gastroscopies and in 79, 8 and 13% of the colonoscopies respectively. Nevertheless bad tolerance did not hinder the completion of the procedure in any case. CONCLUSIONS: The administration of propofol by the endoscopist and the assistant nurse, is an effective and safe method of sedation in patients of low and high-risk as well as in elderly patients. The doses of propofol required for an adequate sedation were lower in patients over 65 years of age and for colonoscopies in which medication was combined.

Adolescent↗
PubMed2005

[Me, the intruder].

Explore the source record for details and available documents.

Procedural Sedation↗
PubMed2003

[Electrolytic disturbances and colonoscopy: bowel lavage solutions, age and procedure].

INTRODUCTION: Colonoscopy and bowel preparation cause a number of serum electrolytes changes. AIMS: To determine the prevalence of these changes in patients who underwent colonoscopy and to identify risk factors for these effects. PATIENTS AND METHODS: Forty five patients undergoing colonoscopy were assessed prospectively. They have been previously randomized to receive either sodium phosphate (NaP) or polyethylene glycol (PEG) as preparation. Serum levels of sodium and potassium were analyzed before colonoscopy, immediately after the end of colonoscopy, and 1 hour thereafter. Serum calcium and phosphorus levels were measured just before colonoscopy. RESULTS: Twenty five patients (55.5%) received PEG and 17 (37.7%) NaP. Three patients (6.6%) did not follow the recommended bowel preparation instructions and were excluded from the study. Five patients (11%) developed hyponatremia, of whom, in 4 cases (8.8%), it occurred after the procedure. Thirteen patients (28.8%) developed hypokalemia, of whom it occurred after the end of the procedure in seven (15.5%). There was a non-significant trend to decreased serum potassium levels 1 hour after colonoscopy in patients prepared with NaP (63.6 vs 36.4%). The multivariate analysis showed that low potassium levels were independently associated with age and NaP preparation. Hypocalcemia was observed in 2 patients (4%) and hypophosphatemia in 8 (18%). Hyperphosphatemia was found in 8 cases (18%). Non-significant increases in phosphorus levels were observed in the NaP group. CONCLUSIONS: Temporal sequences of the development of serum electrolyte disturbances suggest that colonoscopy itself might play a role in the pathogenesis of these changes. Preparation for colonoscopy with NaP and the age of patients are risk factors for the development of hypokalemia.

Adolescent↗
PubMed2001

Characterization of the safety, effectiveness and use of oral sodium phosphate.

OBJECTIVE: The objective of this study was to assess the tolerability, safety and effectiveness of an oral sodium phosphate solution as a colon preparation method prior to colonoscopy, compared to a standard polyethylene glycol preparation. EXPERIMENTAL DESIGN: A cohort-based multicenter, prospective, observational clinical study was conducted. PATIENTS: Twenty-nine centers from all over Spain participated in this study, including a total of 638 patients who met all the inclusion criteria established. RESULTS: The oral sodium phosphate solution has an effectiveness and safety profile similar to the standard poliethylene glycol preparation; however, due to its dosage, it is better tolerated by patients, with a statistically significant difference between both preparations. CONCLUSIONS: Based on the effectiveness, safety and tolerability profile of oral sodium phosphate solution in patients, it can be considered the preparation of choice before colonoscopy, since it allows a fast, effective and safe bowel cleansing in patients without contraindications.

Administration, Oral↗
PubMed1989

[Preneoplastic lesions associated with carcinoma of the stomach: retrospective study of 125 gastrectomy pieces].

A study was made of 125 gastrectomy pieces with gastric carcinoma in which metaplastic and dysplastic changes on the intact gastric mucosa adjacent to the tumor were analyzed. Both incomplete intestinal metaplasia and different types of dysplasia were more frequently and significantly associated with carcinomas of intestinal pattern than with diffuse ones (p less than 0.001). Jass type I dysplasia was more frequent in well-differentiated carcinomas, while Jass type II was more common in relatively undifferentiated tumors, the difference being highly significant (p less than 0.001). Our results and those of other studies in the literature suggest a pathogenic relationship only between preneoplastic lesions and gastric carcinoma of intestinal pattern, which probably includes entities that can be differentiated by pathogenesis to judge from the variations in the dysplastic changes observed.

Aged↗
PubMedDate not supplied

[Percutaneous endoscopic gastrojejunostomy in the Guillain-Barré syndrome].

The nutritional support through an enteral route in patients diagnosed with Guillain-Barré syndrome, may be affected by the digestive alterations derived from the non-autonomic affliction. Even though the percutaneous endoscopic gastro-jejunostomy is still an infrequent technique in intensive-care units, its use in certain patients may ease the application of enteral nutrition. We present a case of Guillain-Barré syndrome, treated with enteral nutrition in an ICU during 100 days, 85 of which were by means of a gastro-jejunostomy tube, with good results.

Aged↗