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Biomedical subjects

S Rouatbi

Publications and source records attributed to S Rouatbi.

5 recordsLinked to original sources
PubMed2006

[Physiological factors influencing pulmonary capillary volume and membrane diffusion].

BACKGROUND: The lung is subject to many physiological changes during life. The aim of this study was to identify factors that influence gas transfer, which depends on membrane diffusion (Dm) and pulmonary capillary blood volume (Vc). METHODS: Dm and Vc measurements were performed at rest in 135 healthy patients divided into three groups according to age and after an exercise in 22 non-trained children. Measurements were made using a simultaneous transfer of 2 gases; nitric oxide (NO) and carbon monoxide (CO). RESULTS: Dm was correlated with height in the adult group and with weight in the elderly group. Vc was not correlated with weight in the three studied groups, but correlated with height in the adult group. Dm and Vc declined with age (p<0.05), For Dm this started at the age of forty whereas a fall in Vc was apparent at sixty. Pulmonary and vascular ageing could explain these results. Sex had no effect on Dm and Vc. Exercise led to a significant rise in Dm and Vc (p<0.05) which was attributed to pulmonary capillary distension and recruitment. CONCLUSION: Knowledge of these physiological changes permits a better understanding of pathological changes.

Adolescent↗
PubMed2004

[Physiological aspects of the decline of pulmonary function with age].

After peaking between the age of 20 and 30 years, pulmonary function declines gradually with age. This decline is related to changes in respiratory dynamics (lung mechanics, gas exchange) and also to non-respiratory factors (e.g. changes in the immune system). This age-related fall in pulmonary function is not linear, for example there is no further decline in mean PaO2 in men and women, nor in the FEV1/FVC ratio in men, afterthe age of 70 years. Caution is required when interpreting changes in pulmonary mechanics in the elderly due to greater variability of reference values in this age group.

Adaptation, Physiological↗
PubMed2003

[Vital capacity and peak expiratory flow rates in a North-African population aged 60 years and over: influence of anthropometric data and parity].

INTRODUCTION: The aims of this study were to calculate predictive equations for respiratory variables (FVC, FEV1, FEF25%-75%, and PEFR) in elderly north-African people and to study the effect of parity on the respiratory function. METHODS: FVC and forced expiratory flows were measured in a "healthy" sample of 186 subjects aged 60 years and over (66% women). The measurements were made in health centres using portable spirometers. Predictive equations were determined by the technique of multiple linear regression using standing height and age as independent variables. The effect of parity on ventilatory function was studied by comparing two groups defined by a parity greater or less than 4. RESULTS: The respiratory variables measured in this elderly north-african population were significantly different from those established references ranges. CONCLUSIONS: High parity is associated with a significant reduction in peak flow rate.

Africa, Northern↗
PubMed2002

[Physiological aspects of the decline of pulmonary function with age].

After peaking between the age of 20 and 30 years, pulmonary function declines gradually with age. This decline is related to changes in respiratory dynamics (lung mechanics, gas exchange) and also to non-respiratory factors (e.g. changes in the immune system). This age-related fall in pulmonary function is not linear, for example there is no further decline in mean PaO(2) in men and women, nor in the FEV1/FVC ratio in men, after the age of 70 years. Caution is required when interpreting changes in pulmonary mechanics in the elderly due to greater variability of reference values in this age group.

Adaptation, Physiological↗