PubMed Health⌕ Search

Biomedical subjects

S Rusconi

Publications and source records attributed to S Rusconi.

94 records · Page 6Linked to original sources
PubMedDate not supplied

[The mentally handicapped: what educational and (pre)occupational future? Study of the Genevan population of mentally handicapped capable of job placement].

Personal and structural variables appear to determine the school, the pre-professional and the professional cursus of 575 mentally handicapped adults living in Geneva. At a personal level, the I.Q. plays the principal role until about the age of 15. As soon as the question of the professional life arises, one has to take other factors into account: secondary disorders, sex and, above all, the social class. At the structural level, the evolution is quite clear: as soon as new institutions are created, they are filled to capacity, leading, year after year, to a greater segregation.

Adolescent↗
PubMedDate not supplied

Disappearance of cryoglobulins and remission of symptoms in a patient with HCV-associated type II mixed cryoglobulinemia after HIV-1 infection.

OBJECTIVE: We report the case of a woman with long-lasting mixed cryoglobulinemic syndrome, who experienced clinical and laboratory remission of her cryoglobulinemia after becoming infected with human immuno-deficiency virus and developing HIV-1 induced immunosuppression. METHODS: Serum cryoglobulin concentrations and the CD4+ cell count were monitored every three months. RESULTS: After the diagnosis of HIV-1 infection, the immunological status of the patient was constantly depressed (CD4+ cell count dropping from 337/microL in January 1991 to 21/microL in June 1994). Serum cryoglobulins were persistently absent over 43 months of follow-up, despite the presence of HCV-RNA. CONCLUSION: In this case, HIV-1 induced immunodeficiency seems to be responsible for the remission of the cryoglobulin syndrome and the disappearance of serum cryoglobulins. These findings indicate that CD4+ T lymphocytes may play a role in regulating the activity of cryoprecipitating rheumatoid factor secreting B cell clones.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

Still's disease in a patient infected with human immunodeficiency virus type I.

An autoreactive cellular immune response may be a part of HIV-1 infection. This autoimmune phenomenon also includes antibodies to collagen that can be associated to arthritis as a clinical condition. In this paper we describe a case of Still's disease in an adult HIV-1 infected patient who presented a marked amelioration in his condition after 15 days of steroid therapy, as well as an improvement of the arthritis. This rare autoimmune condition, which is connected with the disregulation of the immune system, must be taken into account in HIV-1 infected individuals who present with fever of unknown origin.

Adult↗