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Biomedical subjects

S S Gupta

Publications and source records attributed to S S Gupta.

44 records · Page 3Linked to original sources

Histamine content of the digestive tract of a catfish Clarias batrachus (Linn.) in relation to spawning, sex and seasonal variation.

Histamine content of the digestive tract of a catfish Clarias batrachus has been estimated biologically on the atropinized guineapig ileum. A significant decrease of histamine content has been observed with the decrease of gonosomatic index (G.S.I.) during breeding season in female fishes, while no such type of change in histamine content of male fishes during breeding season has been noted. In the summer histamine content of both the sexes was signivicantly lowered in comparison with the histamine content during breeding season in both the sexes. It is concluded that higher histamine content in prespawing female fishes during breeding season may be due to the inhibition of the enzyme histaminase by gonadotrophines. It is also suggested that the route of inactivation of histamine during breeding season may be different in both the sexes, while in summer a common factor may be involved in depletion of histamine content of both the sexes.

Animals↗

Purgative and anthelmintic effects of Mallotus philippinensis in rats against tape worm.

A resin isolated from Mallotus philippinensis (Kamala) caused a significant purgative effect after an oral dose (120 mg/kg) in rats as assessed from the weight of faeces as well as from the surface area of blotting paper soaked by liquid faeces. The anthelmintic effect of the resin was evaluated in albino rats found to be infested with tape worms. The resin in 60 and 120 mg/kg dose had a lethal effect on 35.69% and 78.21% population of tape worms respectively, in small intestine.

Animals↗

Gastrointestinal leiomyomas in a developing country.

Twenty one consecutive patients with leiomyoma of the gastrointestinal tract were studied. Recurrent gastrointestinal bleeding was found in 18 (85.7%) and recurrent intestinal obstruction in 3 (14.3%) patients. The commonest site of the lesion was the stomach followed by ileum, jejunum and duodenum. Barium meal examination and gastrointestinal endoscopy were suggestive of the diagnosis in 8 and angiography in 2 patients. The remaining patients were diagnosed peroperatively. All patients underwent excision and remained asymptomatic on follow up except two patients who had a recurrence of the tumor as leiomyosarcoma.

Adult↗

Acetylcholine content of the brain and visceral organs of the teleostean fish; Heteropneustes fossilis and Clarias batrachus.

The acetylcholine content of various organs of two teleostean fish, Heteropneustes fossilis and Clarias batrachus has been estimated biologically on the eserinized frog rectus muscle. The acetylcholine content in the stomach of both the fish was 0.341 and 0.22 mug/g, respectively. Values were lower than those of other parts of the alimentary tract. The ilia contained the most acetylcholine, being 0.644 and 0.551 mug/g respectively, for the two fish. In the brain, heart, kidney and liver of both the fish, a considerable amount of acetylcholine was detected. Acetylcholine was not found in the spleen of Clarias batrachus, but it was present in the spleen of Heteropneustes fossilis.

Acetylcholine↗