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Biomedical subjects

S S Iyengar

Publications and source records attributed to S S Iyengar.

16 recordsLinked to original sources

Pre-eclampsia.

Explore the source record for details and available documents.

Blood Pressure Monitoring, Ambulatory↗

When choice is demotivating: can one desire too much of a good thing?

Current psychological theory and research affirm the positive affective and motivational consequences of having personal choice. These findings have led to the popular notion that the more choice, the better-that the human ability to manage, and the human desire for, choice is unlimited. Findings from 3 experimental studies starkly challenge this implicit assumption that having more choices is necessarily more intrinsically motivating than having fewer. These experiments, which were conducted in both field and laboratory settings, show that people are more likely to purchase gourmet jams or chocolates or to undertake optional class essay assignments when offered a limited array of 6 choices rather than a more extensive array of 24 or 30 choices. Moreover, participants actually reported greater subsequent satisfaction with their selections and wrote better essays when their original set of options had been limited. Implications for future research are discussed.

Adult↗

Rethinking the value of choice: a cultural perspective on intrinsic motivation.

Conventional wisdom and decades of psychological research have linked the provision of choice to increased levels of intrinsic motivation, greater persistence, better performance, and higher satisfaction. This investigation examined the relevance and limitations of these findings for cultures in which individuals possess more interdependent models of the self. In 2 studies, personal choice generally enhanced motivation more for American independent selves than for Asian interdependent selves. In addition, Anglo American children showed less intrinsic motivation when choices were made for them by others than when they made their own choices, whether the others were authority figures or peers. In contrast, Asian American children proved most intrinsically motivated when choices were made for them by trusted authority figures or peers. Theoretical and practical implications of these findings are discussed.

Child↗

A computer model for hydrodynamic shearing of DNA-further investigation on distribution of break lengths: Part III.

The distribution of breaks along The DNA strand in hydrodynamic shearing is unknown, and there is no real-world experiment which could directly determine this distribution. This paper presents an extension of the simulation model for hydrodynamic shearing of DNA reported in [1,2]. An empirical model is presented showing a good linear relationship between LAMBDA * and number of fragments from each original strand. The average strand length is directly proportional to the number of fragments per strand. The traditional assumption of uniform random breaks along the DNA strand is supported by this model.

Chemical Phenomena↗

A computer model for hydrodynamic shearing of DNA.

A computer simulation model for the hydrodynamic shearing of DNA is presented. In this model the event space consists of a number of positions at which the DNA strand may break. The results of the model compared with the real world result are reported in this paper. Future endeavors to generalize the model would add significantly to the model's value.

Computers↗

A computer model for hydrodynamic shearing of DNA (Gibb's phenomenon): Part II.

This paper presents an extension of the distribution proposed during hydrodynamic shearing of DNA. In the Fourier least square approximation of uniform random distribution or a square wave, Gibb's phenomena occur at the boundaries. The same behavior occurs at the boundaries of the DNA strands undergoing hydrodynamic shearing of DNA. This hypothesis is corroborated by results from a computer simulation of hydrodynamic shearing of DNA. The evidence helps confirm the kinetic experiments of Britten and Kohne [4]. Furthermore the results predict that sequence very near the end (0.2 LAMBDA) should be the most intact.

Computers↗

Low molecular weight heparin for treatment of acute myocardial infarction (FAMI): Fragmin (dalteparin sodium) in acute myocardial infarction.

The benefit of using subcutaneous low molecular weight heparin for the treatment of acute myocardial infarction is not known. The aim of this study was to determine the efficacy of a low molecular weight heparin (dalteparin sodium) for the treatment of acute myocardial infarction in patients not treated with thrombolytic therapy. Twenty-nine cardiological centres from leading hospitals in India participated in this prospective, multicentre, double-blind, placebo-controlled study in two phases which included 1128 patients with acute myocardial infarction. In the acute phase (between day 1 and 3 of admission) all the patients received a weight-adjusted dose of subcutaneous dalteparin (120 IU/kg twice daily). In the second, double-blind phase of acute myocardial infarction, patients were randomised to receive a fixed dose of dalteparin (7,500 IU) or an identical placebo injection for 30 days. A composite primary endpoint of death, reinfarction, recurrence of angina and emergency revascularisation was used. All the 1128 patients with acute myocardial infarction were included in the trial. In the acute phase, the composite primary endpoint was observed in 58 (5.1%) patients. Of 1037 paients who were randomly assigned to receive a fixed dose of dalteparin (n=519) or placebo (n=518), the composite primary event rate was 6.7 percent and 7.0 percent, respectively (RR 0.97; 95% CI 0.62-1.52; p=0.90). To conclude, treatment with dalteparin administered subcutaneously in a weight-adjusted dose of 120 IU/kg twice daily resulted in a lower than expected mortality during the acute phase of myocardial infarction. A lower fixed once daily dose of 7,500 IU during the chronic phase did not confer additional protection.

Aged↗