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S S KALTER

Publications and source records attributed to S S KALTER.

At least 19 recordsLinked to original sources

ISOLATION OF ENTEROVIRUSES FROM THE "NORMAL" BABOON (PAPIO DOGUERA).

Fuentes-Marins, R. (Southwest Foundation for Research and Education, San Antonio, Texas), A. R. Rodriguez, S. S. Kalter, A. Hellman, and R. A. Crandell. Isolation of enteroviruses from the "normal" baboon (Papio doguera). J. Bacteriol. 85: 1045-1050. 1963.-In a study designed to determine whether the baboon (Papio doguera) would be suitable for use as a model of human virus infections, the normal enterovirus flora was determined. Five agents were isolated from 101 stool samples: four from the African group and one from the African-African group. None of the stool samples from the Domestic group of animals was found to contain any agents. On the basis of their biological characterizations (animal source, cytopathic effect, plaque formation, and antigenic relationships), the isolates were separated into two groups. Accordingly, prototype strains AA153 and A13 were designated for the African-African and African groups, respectively. These viruses have not been found to be related to any known human viruses. Their relationship to organisms isolated from other animals, especially primates, awaits study. The failure to detect latent viruses in preparations of baboon kidney cell cultures suggests a relatively "clean" animal which may be used with safety in preparation of vaccine for human administration.

Animals↗

A serological survey of antibodies to selected enteroviruses.

SERA FROM VARIOUS POPULATION GROUPS IN LIBERIA, COLOMBIA, PERU AND SOUTHERN LOUISIANA, USA, HAVE BEEN STUDIED FOR THE PRESENCE OF NEUTRALIZING ANTIBODIES TO THE FOLLOWING ENTEROVIRUSES: poliovirus type 1, Coxsackie viruses B5 and A9, and ECHO viruses E6 and E9. The results obtained indicate that these viruses are world-wide in distribution and that infection (though not necessarily disease) occurs at an early age. Variations in antibody patterns occur, most notably with Coxsackie B5 virus. Environmental conditions apparently influence the spread of virus, but other factors, as yet unknown, may also play an important role in the dissemination of an organism. It is suggested that surveys such as these might be useful to indicate populations in need of particular vaccines.

Antibodies↗

Animal "orphan" enteroviruses.

Since the discovery, some ten years ago, of the pathogenic effect of polioviruses on non-nervous-tissue cells, tissue-culture methods have come to be widely used in virological research. Through these improved techniques for studying viruses, a large number of new cytopathogenic agents have been isolated from the intestinal tract of man. Many of these agents have been obtained from persons suffering from polio-like disease, but others have been isolated from apparently normal persons. The term "orphans" is used to designate those viruses which cannot definitely be associated with any recognized disease syndrome.The existence of these enteric pathogenic human orphan (ECHO) viruses, and their association with clinical disease in certain cases, stimulated interest in their animal counter-parts, which might constitute a serious threat to both human and animal health. In this paper, the author reviews the information at present available on the occurrence of the so-called "orphan" enteroviruses in monkeys, cattle, swine, and other animals in various parts of the world, and discusses the possible interrelationships of these animal viruses with each other and with the human enteroviruses.

Animals↗