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S S Papiha

Publications and source records attributed to S S Papiha.

At least 127 records · Page 7Linked to original sources
PubMed1976

Esterase D and superoxide dismutase polymorphisms in Iraq.

From a study of 320 individuals superoxide dismutase (SOD) variants are shown to be present in Iraq, and it is suggested that this genetic system may be useful for the study of historical population movement in the Middle East. The esterase D gene frequencies show no significant heterogeneity among the different regions of the country.

Esterases↗
PubMed1975

Some hereditary blood factors of the Bengali Muslim of Bangladesh (red cell enzymes, haemoglobins, and serum proteins).

In a sample of Bengali Muslems from Dacca, haptoglobin, group-specific component, haemoglobin, adenosine deaminase, adenylate kinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase, acid phosphatase and several other red cell enzyme types were studied. For most serum protein and red cell enzyme systems the gene frequencies are similar to those in other populations to the west of Bangladesh, but others suggest affinity with populations to the east.

Acid Phosphatase↗
PubMed1975

Serum alkaline phosphatase in patients with multiple sclerosis.

Sera from multiple sclerosis patients show a deficit of intestinal alkaline phosphatase (serum type Pp2) by comparison with normal sera. This is not due to variation in ABO frequency, since the specimens from patients and normals are matched for ABO frequency, and it is not due to differences in secretor frequency, but represents a real dificit for Pp2 in patients with multiple sclerosis, particularly noticeable in group O individuals.

ABO Blood-Group System↗
PubMedDate not supplied

D1S80 distribution in world populations with new data from the UK and the Indian sub-continent.

BACKGROUND: Highly polymorphic genetic markers including variable number of tandem repeats (VNTRs), amplified fragment length polymorphisms (AMP-FLPs) and short tandem repeats (STRs) have been used successfully in disease diagnostics, forensics, paternity analysis and population diversity studies. The D1S80 locus has been extensively investigated in many populations but studies on the UK and Indian subcontinent populations are limited. AIM: This study aims to enlarge our understanding of genetic variation at the D1S80 locus in the populations of the UK and the Indian subcontinent. Also, the spectrum of genetic variation at this locus in world populations is analysed. SUBJECTS AND METHODS: Six geographically and ethnically diverse populations were genotyped for the D1S80 locus using the polymerase chain reaction (PCR) technique. Two UK populations were from the East Midlands and North East England, while Brahmins, Parsis, Sinhalese and Moors represented the Indian subcontinent populations. In addition, allele frequency data of the present study were compared with 78 world populations using different methods of multivariate analyses to document level and extent of genetic diversity. RESULTS: All study populations were in Hardy-Weinberg equilibrium. A trimodal distribution (alleles 18, 24 and 31) was observed in four populations (North East England, East Midlands, Brahmins and Parsis). The Sinhalese and the Moors had different trimodal distributions. The overall heterozygosity and the level of variation are comparable to many Caucasian populations. Multivariate analyses (correspondence analysis and multidimensional scaling analysis) provided similar results in differentiation of major ethnic population groups. CONCLUSIONS: Since D1S80 variation shows considerable homogeneity within a given ethnic group, but marked variation among them, it is a useful anthropological marker for the differentiation of these populations.

Ethnicity↗
PubMedDate not supplied

Study of phosphoglucomutase polymorphism by isoelectric focusing: gene frequencies in the Gaddi tribe of Himachal Pradesh, India.

A total of 254 Rajputs and Brahmins of the Gaddi tribe from the regions of Kangra and Chamba in Himachal Pradesh, north-west India, were examined for red cell PGM1 phenotypes by isoelectric focusing (IEF). All the ten possible phenotypes from the four alleles of PGM1 described by IEF were found in this population. Comparison of gene frequencies in the present two ethnic groups and with the only other study available on Asians from London shows that IEF is another useful biochemical method for the study of population diversity.

Alleles↗
PubMedDate not supplied

Genetic heterogeneity and population structure in north-west India.

Genetic markers consisting of 11 blood group and red cell enzyme systems were investigated in 14 endogamous groups of north-west India. Genetic differentiation among the samples as indicated by FST is appreciable, reflecting the ethnic diversity characteristic of this region. Local variation within each state is lower, indicating a geographical component to the total variation. This variation is refined by calculations of genetic distances, which show that the tribals and low-caste groups are closer together but well separated from high-caste Brahmins and other non-tribal middle castes. There is a slight possibility of disruptive selection, but the analyses suggest that the differences in genetic structure in north-west India are more likely to be due to their breeding structure, differential migration and ethnic affiliation.

Alleles↗