Biomedical subjects

S S Shestopalov

Publications and source records attributed to S S Shestopalov.

3 recordsLinked to original sources

PubMed2006

[Postoperative electrostimulation in abdominal surgery].

A new method of electric stimulation of the gastrointestinal tract in surgical patients is analyzed. The study group consisted of 201 patients after different abdominal surgeries who had undergone electrostimulation procedures in postoperative period. Conventional methods of paresis prophylaxis and treatment were used in 419 similar patients (control group). Electrostimulation was performed during 20-30 min two times a day from the first day after surgery till complete resolution of paresis. It is concluded that direct electrostimulation in postoperative period reduces duration of paresis, number of postoperative pneumonias ( 6-fold and more) and other complications. Postoperative lethality was 3.98% in the study group and 7.87% in the control group.

Adolescent↗

PubMedDate not supplied

[The characteristics of the neuropsychotropic activity of bromantane in laboratory animals].

Bromantan [N-2-(para-(bromphenyl)-N-2-(aminoadamantan)] possesses psychostimulating activity in experiments on animals. With LD50 8100 mg/kg (mice, intraperitoneal injection) activates simple and complicated forms of behavior, induces EEG effects typical of psychostimulators, is an antagonist of substances with a deprivationg neuropsychotropic effect. Bromantan is characterized by a positive effect on mnemonic processes and on obtaining the results of complex operant activity in rats.

Amantadine↗

PubMedDate not supplied

[The therapeutic efficacy and the effect of gidazepam and fenazepam on the psychophysiological status and on the performance of operators with mental disorders at a neurotic level].

The effect of placebo and gidazepam on the state, psychophysiological predictors of the quality of the operator's performance and its results in individuals with neurotic reactions was studied (test dose 20 mg 7-day course, 40 mg daily, 24 individuals), as well as the effect of gidazepam and phenazepam (42 individuals with neurotic and neurosis-like states; gidazepam test doses 20 and 50 mg, 14-day course, 40 and 100 mg daily; phenazepam test doses 0.5 and 1 mg, 14-day course, daily dose 2 mg). The generally accepted methods of clinical and psychophysiological examination were applied. Gidazepam in the doses under study did not yield to phenazepam in therapeutic activity. A single and a course administration of gidazepam improved the parameters of the psychophysiological state and the efficacy of the operator performance in patients with neurotic reactions and in those with neurotic and neurosis-like states. This makes it possible, whenever necessary, to recommend this drug for the treatment of the indicated disorders in the working operators.

Adult↗