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Biomedical subjects

S S Silva

Publications and source records attributed to S S Silva.

18 recordsLinked to original sources

Effect of acetic acid on xylose fermentation to xylitol by Candida guilliermondii.

The effect of acetic acid concentration on xylose-fermentation to xylitol by Candida guilliermondii FTI 20037 was evaluated in semisynthetic medium containing different concentrations of the acid. Increasing acetic acid concentration up to 1.0 g/l favored xylitol yield and productivity, with maximum values of 0.82 g/g and 0.57 g/l.h, respectively. The presence of acetic acid reduced cell production at all concentration. Furthermore, acetic acid was assimilated by the yeast together with the sugars and was depleted from the medium at concentrations of less than 3.0 g/l. The ability of this yeast to assimilate acetic acid suggests that these cells act as agents of medium detoxification. This behavior may lead to a viable microbiological process of xylitol production by C. guilliermondii FTI 20037 using xylose-rich lignocellulosic hydrolysates in which acetic acid is commonly present, causing inhibition of fermentative activity.

Acetates

Modified technique for total cavopulmonary connection.

The laterolateral anastomosis between the superior vena cava and the pulmonary artery trunk is presented as a modified technique for total cavopulmonary connection. This procedure was successfully performed on a 9-year-old girl, associated with the exclusion of the right atrium, for the treatment of tricuspid atresia and transposition of the great arteries.

Anastomosis, Surgical

Babesia bovis: infectivity of an attenuated strain of Brazilian origin for the tick vector, Boophilus microplus.

In order to verify the infectivity and transovarian transmission of one strain of Babesia bovis of Brazilian origin, attenuated by repeated passages in splenectomized calves to the biological tick vector, Boophilus microplus, an inoculation of that strain was performed in hemoparasite-free calves infested with hemoparasite-free ticks. Subsequently, engorged female ticks were collected to examine hemolymph and progeny for presence of developing stages of Babesia bovis. Using an optical microscope, intrahemocytic merozoites were observed in female hemolymph on the second and fourth days, respectively, after ticks dropped from calves. By histological observation of F1 larvae, after more than 24 h of adherence on calves, sporokinetes and small merozoites were present in the samples of hemolymph. These results confirmed the maintenance of infectivity by the vaccine strain attenuated after 26 passages for tick Boophilus microplus.

Animals

Mitral valvuloplasty with a new prosthetic ring. Analysis of the first 105 cases.

From October 1987 to March 1993, 105 patients were studied who have undergone valvuloplasty with an open ring. They ranged from 5 to 79 years (mean 30); 33 (31.4%) were under 16. All patients had mitral insufficiency, alone in 62 (59.0%) and associated with mitral stenosis (double mitral lesion) in 43 (41.0%). In the majority of the cases, the aetiology was rheumatic (78.1%); active in 10 (9.5%) patients. Three patients (2.9%) were in class II, 42 (40.0%) in class III, 57 (54.3%) in class IV and 3 (2.9%) in class V. Ten patients (9.5%) had isolated ring implantation while the remaining underwent associated procedures on the leaflets, chordae and papillary muscles. There were two (1.9%) hospital deaths, and six patients (5.7%) had to be reoperated. On the 30th (mean) postoperative day, 75 (71.4%) patients were reevaluated by catheterization, echo Doppler or both to confirm the effectiveness of the techniques employed. The mitral valve was functioning normally or with mitral regurgitation + in 63 (84.0%) patients, mitral regurgitation + + in 2 (2.7%), mitral regurgitation + + + in 5 (6.7%), mitral stenosis + in 4 (5.3%), and mitral stenosis + + in 1 (1.3%) patient. The results were therefore considered excellent in 63 (84.0%) patients with either normal mitral valve or mitral regurgitation +, good in 6 (8.0%) patients with mitral regurgitation + + and/or mitral stenosis +, and poor in 6 (8.0%) patients with mitral regurgitation + + + and/or mitral stenosis + +. Two deaths (1.9%) occurred within the first 7 months of follow-up. Patients were evaluated clinically 1-67 months postoperatively (mean 27):90 (85.7%) were in class I, 4 (3.8%) in class II, 4 (3.8%) in class III and 1 (1.0%) in class IV.(ABSTRACT TRUNCATED AT 250 WORDS)

Actuarial Analysis

[Use of tranexamic acid for bleeding control in myocardial revascularization].

PURPOSE: To compare two groups of 80 patients undergoing to myocardial revascularization with the use of antifibrinolytic drug tranexamic acid and its efficacy in reduce bleeding and blood transfusion. METHODS: Prospective analysis of two groups of 80 patients. Group A-no antifibrinolytic therapy (dec 91-may 92) and group B-fibrinolytic therapy-tranexamic acid-10g EV (jun-dec/92). Quantification of mediastinal drainage over 12h as well as the blood or derivatives received at the same time. RESULTS: Hospital mortality: group A-3.8%, group B-2.5%. Drainage (12h): group A-602 +/- 547 ml and group B-260 +/- 260 ml (p < 0.001). Blood transfusion (12h): group A-1,782 +/- 1,163 ml and group B-1,105 +/- 839 ml (p < 0.001). COMPLICATIONS: group A-two cases of intraoperative myocardial infarction, one episode of jaundice; group B-one case of intraoperative MI, one reoperation for bleeding control, one episode of jaundice, one of renal insufficiency, two mediastinitis and one seizure. The mean hospitalization time was ten days in both groups. CONCLUSION: Tranexamic acid was an effective drug in bleeding control and in reducing blood transfusion in the postoperative of patients submitted to myocardial revascularization.

Adult

[Surgical correction of anomalous venous connection of the left lung without extracorporeal circulation].

Surgical correction of anomalous pulmonary venous connection from the left lung to the innominate vein (through a vertical vein) without cardiopulmonary bypass, was performed in two patients, with excellent evolution. After median sternotomy, the ascending vertical vein was cut obliquely close to the vein, and connected to the left atrial appendage. In the postoperative period, the patients were in NYHA class I and the hemodynamic study showed normal venous drainage from the left lung to the left atrium.

Adolescent

[A new reconstructive technique in cases of mitral insufficiency caused by the elongation of the chordae tendineae of the anterior cusp. A case report].

A new technique is proposed for mitral incompetence due to elongated chordae tendineae of the anterior leaflet. It consists in shortening the chordae tendineae of the leaflet level. First, we make a longitudinal orifice in the anterior leaflet just near its free edge and the elongated chordae tendineae. Through the orifice and with the help of a micro nerve hook we pull the elongated chordae the necessary to keep the anterior leaflet in the same level of the posterior leaflet. The orifice is then closed with a polipropilene 5-0 suture. The mitral annuloplasty was performed with a Gregori IMC prosthetic ring. The excellent clinical and laboratorial data suggest that mitral insufficiency due to elongated chordae tendineae can be corrected by this technique.

Adolescent

[Prevalence of mouth mucosa changes in 7- to 12-year old students].

The present study had the purpose to evaluate the clinical diagnosis of the oral lesions observed on children. The author examined 1396 children and observed 1670 different alterations. The result were analysed and it is discussed the most prevalent lesions. It is also emphasized the role of the Dentists in performing a more detailed examination in order to reach a better diagnosis and indicate the corresponding preventive nd therapeutic measures.

Black People

[Amalgam tattoo].

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Adult