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Biomedical subjects

S Sabri

Publications and source records attributed to S Sabri.

35 records · Page 2Linked to original sources
PubMed1971

Sexual function following aortoiliac reconstruction.

Impotence due to atherosclerotic disease of the aorta and iliac arteries presents as failure to achieve erection. Sterility after aortoiliac reconstructive surgery is more common and presents as inability to ejaculate. If the superior hypogastric sympathetic plexus (presacral nerve) is preserved, sexual function can be maintained in 90% of cases.

Adult↗
PubMed1971

Prevention of early postoperative deep vein thrombosis by intermittent compression of the leg during surgery.

A clinical trial is described in which the effect of intermittent compression of the lower limb during surgery on the incidence of early postoperative deep vein thrombosis was assessed. Deep vein thromboses were diagnosed by the (125)I-fibrinogen uptake test. Peroperative intermittent compression was achieved by means of an inflatable plastic splint coupled to a pneumatic controller. By compressing only one leg of each patient, each patient acted as his own control.With a sequential statistical analysis, 39 patients were required to pass the 5% level of significance. Eleven thrombi were detected in the control (uncompressed) legs and two occurred in the compressed legs; one of the latter was bilateral. The investigation shows that increasing the pulsatility of the venous flow in the leg is a potent prophylactic against postoperative deep vein thrombosis.

Adult↗
PubMed1971

Effects of externally applied pressure on the haemodynamics of the lower limb.

The effects of externally applied pressure of 5-150 mm Hg on the haemodynamics of the leg of dog and man were investigated. The criteria used for the assessments included femoral arterial and venous blood flow as well as vascular hydraulic conductance. The results indicated that external pressure of 5 mm Hg results in a very small non-significant increase in the femoral arterial and venous flow. Higher external pressure of 15 mm Hg or more significantly reduces the femoral arterial and venous flows as well as the vascular conductance. It therefore seems that compression produced by bandaging in horizontal supine subjects has little or no haemodynamic value and may prove to be harmful unless carefully controlled.

Animals↗
PubMed1971

Passive flexion and femoral vein flow: a study using a motorized foot mover.

The effect of rhythmic passive flexion of the foot on femoral vein blood volume flow rate has been investigated in 11 patients undergoing surgery for varicose veins. With rates of flexion varying from 24 to 50 per minute and with amplitudes varying from 20 degrees to 50 degrees it has been shown that the peak femoral vein flow can be increased to twice its normal value and that its pulsatility can be increased elevenfold. These increases are proportional to both the rate and the amplitude of the flexion, the maximum occurring, theoretically, when the foot is flexed +/-28 degrees about a line perpendicular to the leg.The investigation has further shown that the effects of sustained passive flexion are maintained, without appreciable dimunition, for 30 minutes and that the maximum increases are produced in those patients who have the lowest resting flows. It is suggested that per-operative passive flexion of the feet may be a good prophylactic against postoperative deep vein thrombosis.

Blood Flow Velocity↗
PubMed1971

Prevention of early postoperative deep vein thrombosis by passive exercise of leg during surgery.

A clinical trial assessed the effect of passive exercise of the lower limb during surgery on the incidence of early postoperative deep vein thrombosis. Thrombosis was diagnosed by means of the (125)I-fibrinogen uptake test. Passive exercise of the lower limb during the operation was achieved by using a motorized foot mover designed for use on supine subjects, and by pedalling only one leg each patient acted as his own control.In a sequential statistical analysis, 47 patients were required to reach the 5% level of significance. Thrombosis was detected in 11 control (unpedalled) legs alone, and in only one pedalled leg alone. Two patients developed thrombosis bilaterally. The investigation shows that the incidence of early thrombosis in legs which were exercised during surgery was reduced by 77%.

Adult↗
PubMedDate not supplied

Influence of surface charges on cell adhesion: difference between static and dynamic conditions.

We tested the hypothesis that nonspecific repulsion, as a result of electrostatic forces and (or) steric stabilization effects, impaired adhesion more efficiently under dynamic than under static conditions. Cells from the human monocytic line THP1 were plated on a glass surface. Spherical particles bearing monoclonal antibodies specific for antigens expressed by THP1 cells (CD11b, CD18, CD35, CD64) were then added and adhesion was quantified. The effect of neuraminidase treatment of THP1 cells was also studied. Adhesion was then measured in a flow chamber under low shear flow (wall shear rate was 11 or 22 s-1), allowing a quantitative determination of cell adhesion frequency. The following conclusions were obtained: (i) under static conditions, neuraminidase treatment had little effect on adhesion (only CD18-mediated interaction was significantly increased at 4 degrees C after enzyme treatment); (ii) under dynamic conditions, neuraminidase treatment significantly increased binding; (iii) surprisingly, there was no clear relationship between the length of adhesion molecules involved in the interaction and binding efficiency; and (iv) such parameters as cell shape and topographical distribution of adhesion molecules may strongly influence adhesion under flow. It is concluded that a dynamic reorganization of the pericellular matrix following intercellular contact may play an important role in regulating adhesion.

Cell Adhesion↗
PubMedDate not supplied

Some risk factors for hypertension in the United Arab Emirates.

A case-control study evaluated the relationship between hypertension and socioeconomic and lifestyle factors in Al-Ain city. The survey included 426 hypertensive adults aged 20-65 years attending urban and semi-urban clinics and a randomly selected sample of 436 normotensive controls. Hypertension among cases was higher for men, age 40-49 years, non-UAE nationals, urban living, currently married, having children, illiterate, administrative/professional job, living in traditional house and low income. There were significant differences between cases and controls with regard to obesity, raised cholesterol level, low physical activity and family history of heart disease, kidney disease or diabetes. Multivariate logistic regression analysis revealed that obesity, medium/high income, history of diabetes, low physical activity and having 3+ children were significantly associated with hypertension.

Adult↗