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Biomedical subjects

S Sahmay

Publications and source records attributed to S Sahmay.

6 recordsLinked to original sources
PubMed1986

Uterine activity during sleep.

REM-related increases in uterine activity were found in 10 healthy young adult volunteer subjects. Contraction baseline pressures were elevated compared with NREM sleep, stage 2 sleep, stages 3 and 4 slow wave sleep (SWS), and stage 0. Contraction amplitudes during REM sleep were greater than those during SWS and stage 0, while contraction rates differed only between REM sleep and SWS. The results strongly indicated a cycle of genital activity in women that parallels the penile erection cycle in men. The implications of this finding and suggestions for future research are discussed.

Adult↗
PubMedDate not supplied

Maternal, umbilical, uterine and amniotic prostaglandin E and F2 alpha levels in labour.

This paper confirms the important role played by prostaglandins in the induction of uterine contractions and the initiation of human labour, although the exact mechanism of action in labour remains unclear. Seventeen pregnant women at term were studied. Of these nine were in labour and the remainder underwent elective section. Prostaglandin E and F2 alpha levels were measured in maternal, umbilical and uterine plasma and amniotic fluid by radioimmunoassay. Levels of prostaglandin E were generally higher than prostaglandin F2 alpha but they were significantly lower in maternal and uterine plasma. Levels of prostaglandin F2 alpha were significantly higher in maternal plasma during labour. The highest levels of prostaglandin were found in amniotic fluid. Measurements indicate that the decreasing ratio of prostaglandin E/F2 alpha is more important in the initiation of labour than absolute levels of either prostaglandin.

Adult↗
PubMedDate not supplied

Effect of different types of intrauterine devices on intrauterine activity.

OBJECTIVE: To compare the effects of various IUDs on intrauterine activity. PATIENTS AND METHODS: 57 women volunteers aged 18 to 25 in the outpatient clinic of the Department of Obstetrics and Gynecology at Cerrahpasa Medical Faculty of Istanbul University were included in the study. All were in good health and menstruating normally. The subjects were introduced to different types of IUDs on the fifth to eighth days of their menstrual cycle. Intrauterine activities with and without naproxen were recorded, for at least 20 minutes each time, with a micro-tip transducer before insertion, just after insertion, and 1 month later. RESULTS: Intrauterine activity increased just after insertion of both IUDs and disappeared 1 month later in copper-T wearing women, but persisted in multiload wearers. Naproxen seemed to be useful in preventing intrauterine activity caused by the IUD. CONCLUSIONS: The IUD itself causes an increase in intrauterine activity which is preventable by naproxen, suggesting the possible role of prostaglandins. Persistence of intrauterine activity depends upon the type of device. Optimal designing of IUDs is required to decrease side effects and make them more acceptable.

Adolescent↗
PubMedDate not supplied

The effect of intrauterine insemination on uterine activity.

Intrauterine insemination (IUI) may lead to very painful uterine cramps, which are due to the effect of the prostaglandin (PG) content of human semen. The purpose of this study is to present the reactivity of the human uterus to the placement of raw semen in the intrauterine space and to evaluate the related response patterns. A statistically significant uterine activity change was observed between the periods before and after intrauterine insemination. Three minutes after IUI, an increase in uterine activity was observed; it became most prominent at five to ten minutes. This stimulation was sustained for 30 minutes and decreased gradually. Although there is an increase in uterine activity following intrauterine insemination, neither pelvic pain nor abdominal discomfort was reported. According to this observation, we suggest that a semen volume of 1 mL might be used safely for intrauterine insemination.

Adult↗
PubMedDate not supplied

Endometrial biopsy findings in infertility: analysis of 12,949 cases.

OBJECTIVE: Endometrial biopsy has been an important way of assessing infertile couples for several years. In this review of a wide-ranging series of endometrial biopsies of infertile couples in the Turkish population it was our aim to find the distribution of results according to the years 1956-1966, 1967-1980, 1981-1992. SETTING: University hospital. SUBJECTS: 12,949 endometrial biopsies, referred to our gynecological pathology laboratory for infertility investigation between 1956 and 1992. METHOD: Patient report files from pathology laboratory data, analyzed retrospectively. The assessment of the biopsies is made by the same pathologist. RESULTS: 78.8% of cases had primary infertility, 21.2% secondary. Most of them were in the age group 26-35 years (48.8%). 37.58% of cases were found to show normal secretory endometrium, 20.95% proliferative endometrial changes, and 28.22% signs of luteal phase defect (LPD). Other local endometrial factors were also encountered, but in 1.79% the sample was considered insufficient for diagnosis. Moreover, in nine cases, malignancy was diagnosed with the help of endometrial biopsy. During the study period, cases of normal secretory endometrium and tuberculous endometritis were observed to decrease and LPD to increase significantly. It is worthy to note that in only 28 (0.21%) cases had endometrial biopsies been performed during a pregnancy cycle. CONCLUSION: We conclude that endometrial biopsy not only shows the hormonal response of endometrium but gives additional information about the local factors of endometrium concerning atrophy, specific and non-specific infections, and malignancy.

Adolescent↗