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S Sakada

Publications and source records attributed to S Sakada.

At least 37 records · Page 2Linked to original sources
PubMed1986

Morphological study of the sensory innervation of the rat labial mucosa.

The sensory innervation of the rat labial mucosa was investigated by means of methylene blue vital staining and osmic acid staining. Sensory receptors in this region were of three kinds (free nerve endings, encapsulated corpuscles and bush-like nerve endings) which constituted separate sensory units respectively. The encapsulated corpuscles were observed in the deep part of lamina propria, and distributed mainly in the margin of labial mucosa. Almost all (78.8%) of encapsulated corpuscles were of a simple type which had a non-branched axon terminal. No clew-like type corpuscles or glomerular-Meissner corpuscles were observed. The bush-like nerve endings were located in the lamina propria close to the epithelium, and localized in the central part of labial mucosa where the formation of papillae was remarkable. The density of the encapsulated corpuscles in the entire mucosa was 3.5-5.3/mm2, and that of the bush-like nerve endings in the densely distributed area was 38.9-60.6/mm2.

Animals↗
PubMed1986

Sensory innervation of gingival and alveolar mucosa of the house musk shrew (Suncus murinus).

The lingual gingival and the alveolar mucosa of mandible of the house musk shrew (Suncus murinus) were stained by methylene blue vital staining or osmic acid staining, and mounted as whole thickness preparations. The sensory innervation and the distribution of sensory receptors were investigated with a light microscope. The nerve fibers supplying these regions derive from the sublingual nerve, which ascend in the mucosa as they branch out. Sensory receptors found in the present study are of four kinds; free nerve endings, bush-like nerve endings, Merkel cell-neurite complexes and encapsulated corpuscles. The Merkel cell-neurite complexes were scarce and localized in the upper margin of gingival mucosa. The bush-like nerve endings were distributed preferentially in the alveolar mucosa, in which their maximum density was 9-23 per mm2. Among the organized receptors, the encapsulated corpuscles appeared most frequently throughout the mucosal area investigated, and their maximum density amounted to 27-56 per mm2 in the gingival mucosa. These corpuscles were relatively small and poorly differentiated. Although the bush-like nerve endings and the encapsulated corpuscles were fewer in the third molar region, there was no obvious regional difference in their distribution densities from the premolar region to the second molar region.

Animals↗
PubMed1985

Slow-adapting responses of the Pacinian corpuscles of cat planta.

Slow-adapting impulses were recorded from the single nerve fiber innervating the Pacinian corpuscle of the cat planta, which was stimulated by constant pressure. Slow-adapting Pacinian corpuscles responded to both low-frequency (0.1-0.01 Hz) and high-frequency (400-800 Hz) vibrations. Simultaneously performed electron microscopy showed that there were no definite ultrastructural differences between slow- and fast-adapting Pacinian corpuscles.

Adaptation, Physiological↗
PubMed1984

Blood-nerve barrier in the Vater-Pacini corpuscle of cat mesentery.

Correlated thin-section, freeze-fracture and tracer examinations were used to examine the blood-nerve barrier of the Vater-Pacini corpuscles in cat mesentery. A laminar inner core and a multilayered outer core enfolded the terminal nerve fiber of the corpuscle. The lamellar cells of both cores were characterized by numerous vesicular membrane invaginations. Freeze-fracture images and tracer experiments employing lanthanum nitrate proved that these invaginations are static structures mediating in neither active pinocytosis nor the transcellular transport of metabolites. In both inner and outer cores, lamellar cells were connected to one another by tight junctions of either the zonula or the fascia type, that occurred between lamellar-cell processes within the lamella and between the cells of adjacent lamellae. Intravascularly applied lanthanum lay at the outermost regions of the corpuscles without entering their internal zones, apparently because lamellar-cell tight junctions hindered further penetration. The results of our investigations suggest strongly that the Vater-Pacini corpuscle lamellae enfolding the nerve terminal form an effective diffusion barrier against the permeation of tissue fluids, thus preserving the corpuscle internal circumference.

Animals↗
PubMed1981

Distribution of sensory nerve endings in the labial mucosa of the mouse.

The distribution of sensory nerve endings in the labial mucosa of the mouse was investigated by the vital methylene blue staining method. Encapsulated corpuscles were distributed uniformly throughout the mucosa, whereas bush-like nerve endings were localized in the area along the median line where the mucosal epithelium showed a considerable thickness. The number of the encapsulated corpuscles per individual was 72-133, and that of the bush-like nerve endings was 131-248.

Animals↗