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Biomedical subjects

S Saleem

Publications and source records attributed to S Saleem.

28 records · Page 2Linked to original sources
PubMed1993

Median-radial latency difference: its use in screening for carpal tunnel syndrome in twenty patients with demyelinating peripheral neuropathy.

The median-radian latency difference (MRLD) has been advocated as a screen for mild carpal tunnel syndrome (CTS); however, its validity in the face of even mild peripheral neuropathy is questionable. The MRLD of 20 consecutive individual referred with electrodiagnostic evidence of demyelinating peripheral neuropathy was obtained using standard techniques. The MRLD was statistically prolonged in 85% of the subjects without corroborating evidence of CTS (p < .05). Additionally, statistically significant (p < .05) differences were noted between the percentage of prolonged latencies of the radial sensory (50%) and the median sensory (100%) and all sensory nerves (97%). This investigation suggests that superficial radial nerve involvement in demyelinating peripheral neuropathy occurs later than other sensory nerves. This data indicates that though the MRLD may serve as a sensitive screening method for CTS, it has a low specificity therefore, a more extensive evaluation for mild peripheral neuropathy is always indicated.

Adult↗
PubMed1992

Hodgkin's disease in children.

This study provides information about histological types of Hodgkin's disease (HD) among children of Pakistan. Hodgkins disease constitutes 12 per cent of all pediatric malignant tumours. The peak incidence is between 6 and 10 years. The male to female ratio is 5.25:1. The majority (78 per cent) present with cervical lymphadenopathy. Mixed cellularity (MC) is the commonest histological type. In the developed countries nodular sclerosis (NS) and lymphocyte predominant (LP) subtypes are more common, and which have better prognosis. The developing countries have a higher incidence of poor prognostic subtypes. Our study indicates a situation intermediate between the two.

Child↗
PubMed1989

Thrombotic thrombocytopenic purpura: a brief review of recent literature.

Thrombotic thrombocytopenic purpura is a disease characterized by hemolytic anemia, thrombocytopenia, and neurological symptoms. Platelet thrombi in small vessels are formed as a result of endothelial injury or primary platelet aggregation or both. Etiology and pathogenesis, however, are not completely understood. Therapy, at one time nonexistent, has progressed to include plasma exchange, steroids, antiplatelet drugs, splenectomy, vincristine, and gamma globulin, thus improving the prognosis significantly over that of the mid-1960s.

Humans↗
PubMed1978

Neurologic complications of acute myelomonoblastic leukemia of four years' duration.

An adult with acute nonlymphoblastic leukemia involving the central nervous system is presented. Unusual features included: (1) Focal signs and radiographic evidence of sagittal sinus occlusion early in the course of disease; (2) progressive meningeal, cranial nerve, and spinal nerve involvement despite a 4-year bone marrow remission; (3) intracerebral tumor formation, and (4) retrobulbar optic neuritis associated with microscopic findings of herpeslike viral particles. The incidence of clinically overt neurologic disease in adults with acute nonlymphoblastic leukemia seems to have increased in tandem with improved chemotherapy. The prophylactic treatment of the central nervous system during prolonged remission of adult acute nonlymphoblastic leukemia may prove of benefit to these patients.

Adult↗