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Biomedical subjects

S Salman

Publications and source records attributed to S Salman.

At least 55 records · Page 3Linked to original sources

Attenuation of gastric lesions by psychological aspects of aggression in rats.

Rats that fought with each other in response to electric shock showed reduced gastric lesions in comparison with animals that received the same shocks alone so that fighting behavior did not occur. Also, gastric lesions were similarly reduced in animals that fought even though they could not physically contact one another because of a barrier between them, so that the "protective" effect of fighting derived from release of, or display of, fighting behavior and did not require physical combat. A second experiment showed that animals that received shock together but did not engage in fighting behavior showed no reduction of gastric lesions, so that the protective effect of fighting was not an artifact of animals receiving shock together. Possible explanations for why fighting behavior reduces gastric lesions are discussed.

Adaptation, Psychological↗

Heart rate variability in diabetes patients.

Diabetes mellitus can cause cardiovascular autonomic neuropathy and is associated with increased cardiovascular deaths. We investigated cardiovascular autonomic neuropathy in diabetics and healthy controls by analysis of heart rate variability. Thirty-one diabetics and 30 age- and sex-matched controls were included. In the time domain we measured the mean R - R interval (NN), the standard deviation of the R - R interval index (SDNN), the standard deviation of the 5-min R - R interval mean (SDANN), the root mean square of successive R - R interval differences (RMSSD) and the percentage of beats with a consecutive R - R interval difference > 50 ms (pNN50). In the frequency domain we measured high-frequency power (HF), low-frequency power (LF) and the LF/HF ratio. Diabetes patients had lower values for time-domain and frequency-domain parameters than controls. Most heart rate variability parameters were lower in diabetes patients with chronic complications than in those without chronic complications.

Adult↗

[Uncoordinated urination syndrome].

Fourteen male and female patients aged 8 to 21 (mean 12.57 years) underwent clinical and urodynamic evaluation. These patients had different lower urinary tract symptoms, and flow changes and increased perineal muscle activity during voiding were demonstrated urodynamically. The urodynamic work up consisted of flowmetry, cystomanometry, detrusor pressure-flow test, videocystourethrography and electromyography of the periurethral sphincter. The urinary symptoms were nocturnal enuresis in 6 cases (42.85%), urinary infection in 6 (42.85%), difficulty in voiding in 4 (28.57%), urgency incontinence in 4 (28.57%), voiding urgency in 2 (14.28%) and diurnal urgency and frequency in 1 case (7.18%). The following 3 voiding bladder behaviour patterns were observed; 1) involuntary micturition from bladder instability (7 cases, 50%), 2) micturition from voluntary bladder contraction (2 cases, 14.28%) and 3) absence of bladder contractile activity with voiding achieved using the abdominal muscles (5 cases, 35.71%). Decompensated voiding was observed in 21% of the overall group. Of these, 75% belonged to the group that used the abdominal muscles to void. Dilatation of the proximal or prostatic urethra was frequently accompanied by bladder instability (57%). The urodynamic data may be useful in determining the outcome of treatment.

Abdominal Muscles↗

[Action of calcium antagonists on ureteral dynamics].

We have investigated the action, in vivo, of a calcium antagonist on pyelouretheral dynamics. A surgical model consisting of a bilateral subcutaneous nephrostomy was used, which permits repeated studies in the same animal and simultaneous collection from both pyelouretheral tracts. Anterograde perfusion of a 1.5 ml/min flow gives rise to 7.6 +/- 2.3 contractions per minute of variable amplitude between 12.4 +/- 5.6 mm Hg. Verapamil, in intravenous 5-mg application, significantly reduces (P less than 0.05) the number of contractions per minute but does not mitigate or block the stimulus to a subsequent Norepinefrina injection. We conclude that Verapamil has a moderate but significant effect on pyelouretheral dynamics. We comment on the effect that this drug may have on the pyelouretheral tract when used for hemodynamic purposes and on its potential use in various urological affections.

Animals↗