Combined chemotherapy of multibacillary leprosy patients.
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Biomedical subjects
Publications and source records attributed to S Samuel.
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Mouse foot pad testing for primary dapsone resistant leprosy was performed in 15 patients. 13 were resistant (87%). Two patients below 10 years were living with lepromatous leprosy mothers, one male aged 21, was born in Kokana leprosarium and ten others gave no history of known contact of leprosy.
Between 1980-1982, 56 patients suspected of developing dapsone resistant leprosy were seen at the skin clinic of Anandaban Leprosy Hospital and Kokana Leprosarium. Out of 56, 16 control mice had no growth. 29 patients (72.5%) were proved resistant by Mouse foot pad tests.
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Enzymuria observed in PCM, especially in severe cases, does not seem to be a simple reflection of the increased serum values and suggests renal involvements. A number of factors among which are :- lowered clearance threshold for certain enzymes as well as rapid wear and tear or renal cells seem to participate in the causation of such enzymuria. Urine enzyme analysis may reflect the extent and state of renal pathology among different forms of PCM.