Synchronizing and desynchronizing fastigial influences on the electrocortical activity of the cat, in acute experiments.
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Biomedical subjects
Publications and source records attributed to S Sapienza.
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In adult semi-chronically implanted sedated cats discharges of single rubrospinal (RS) neurons were tested for selective activation of movement-evoking foci within pericruciate cortex (CX; area 4) and anterior division of cerebellar interpositus nucleus (IN). It was found that a very high incidence of neuronal responses was obtained only when stimulating IN and CX foci which controlled the same joint with respect to that moved from activation of the rubral foci including the recorded neurons. In these cases very frequent convergence phenomena were observed by activating IN and/or CX foci. Analysis of response patterns showed that RS neurons included in a focus controlling a given muscle were excited by IN foci for the same muscle (agonist foci) and inhibited from IN foci for the antagonist muscle (antagonist foci). In contrast, the same RS neurons were inhibited by agonist CX foci and excited by antagonist CX foci. Such an organization suggests that the motor cortex plays a competitive role in modulating the action of the interposito-rubrospinal system.
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Postoperative follow-up is the logical consequence of cancer treatment, but colorectal cancer follow-up does not achieve all its goals. These unfavourable findings induced us to assess whether follow-up also causes negative psychological stress in our colorectal cancer patients. In this trial 100 colorectal cancer follow-up patients were asked to compile three questionnaires: 1) the McGil Pain Questionnaires; 2) Profile of Mood Status; and 3) Locus of Control. The questionnaires were handed to the patients at follow-up and were compiled immediately. In addition, the patients were asked to answer the firsts two tests spontaneously 30 days after follow-up and mail the questionnaires. Our results showed that only 41% of the patients complied the tests 30 days after follow-up. The scores for pain and mood disorders were greater in women, especially during the "before follow-up" period. The third test revealed a prevalence of subjects with internal-type reinforcement. Our data revealed that: 1) patients tend to repress the problem; 2) women are affected by greater stress and anxiety; 3) subjects with internal-type reinforcement have a positive attitude during follow-up and this enables the ego to bear the anguish, process it and dilute it to anxiety, thus favouring future life experiences.
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