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Biomedical subjects

S Savić

Publications and source records attributed to S Savić.

At least 19 recordsLinked to original sources
PubMed1995

[Disorders of consciousness in trauma patients].

238 patients with multiple trauma hospitalized in the Intensive Care Unit of the Zagreb General Hospital during 1993 and 1994 were analyzed. They were grouped with respect to the type of their injury. The first group was composed of patients with isolated head injury. The second group was made up of patients with multiple trauma and head injury. Patients with multiple trauma but without head injury were inserted into group three. 138 patients were comatose (GCS < 8) and had to be reanimated. 143 patients underwent an urgent surgical procedure. Assisted ventilation over 24 hours needed 180 patients (average of 11,4 days). The most common complications were respiratory: pneumonia developed 60 and ARDS five patients. The rate of mortality was 35,9% (65 patients died.

Coma↗
PubMed1992

EEG arousal and cardiovascular reactivity in professional drivers: the glare pressor test.

Patterns of electroencephalographic (EEG) and polygraphically recorded cardiovascular (CV) reactivity to the glare pressor test (GPT) were compared in 19 healthy, young male professional drivers and eight non-driver controls. After the first headlight impulse, 15 drivers showed persistent blockade of spontaneous alpha activity or complete desynchronization. This was accompanied by a significant fall in digital pulse amplitude and a significant rise in diastolic blood pressure (BP) (7.3 +/- 9.5 mmHg). Most drivers recovered baseline alpha activity and showed milder diastolic BP and digital pulse changes after the final (5th) glare impulse. However, in two drivers this last glare stimulus elicited the most pronounced changes: in one case a rapid onset of ventricular extrasystoles and in the other, maximal rise in diastolic BP, together with a persistently desynchronized EEG. No significant effects of the GPT upon central and CV indices were found in the control group. These results indicate that drivers show cardiovascular hyperreactivity to the GPT, with strong central arousal as expected during night driving when an on-coming headlight can represent impending danger and the need for accurate and timely responses to avoid a collision. Once optimal stimulus parameters for routine application are determined, the glare pressor test with EEG and polygraphic recording will offer a clinically useful, standardizable method for evaluating the connection between central mechanisms and CV reactivity in professional drivers, a cohort of patients whose occupational activity epitomizes mentally stressful work, and who are at high cardiac risk.

Adult↗
PubMed1982

[Ophthalmological and angiographic findings in workers exposed to carbon disulfide (author's transl)].

Microaneurysms are important in the diagnosis of vascular changes caused by carbon disulfide. They can be diagnosed by ophtholmoscopy, angiography or angioscopy. In our opinion even a careful ophthalmoscopic investigation is sufficient for diagnosis, so that angiography is not absolutely necessary for any mass survey. The incidence of microaneurysms correlates with the duration (both daily and total) as well as with the intensity of exposure to carbon disulfide. The quantity correlates closely with the intensity of exposure. The incidence of microaneurysms is not correlated to age; however it was found to be highest in 40-50-year-old men working with staple fibers, whereas in the spinning department it occurred in 50-55-old men. Microaneurysms are found equally frequently in active workers and invalids. There was no difference between the two groups with regard to degenerative changes of the macula. However, the changes found in the eyes of men from the staple fiber department were more pronounced than in those from the spinning department.

Aneurysm↗