So what happens under the DTI marketing initiative scheme?
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Biomedical subjects
Publications and source records attributed to S Scott.
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This paper draws on the work of the Women Risk and AIDS Project (WRAP) which was undertaken by the authors working collectively. It reports on data from a sociological study of the sexual beliefs and practices of two samples each of 75 young women between 16 and 21 in the cities of London and Manchester in the UK. The period of data collection was 1988-1990. The paper sets out the methods used by the WRAP team and locates this research process within wider debates about feminist theory and methodology. There then follows a discussion of the main research findings--relating to the respondents sexual practice--which are then illustrated in some detail in relation to the themes of 'risk and trust' and 'power and empowerment'. Based on these findings conclusions are drawn about the need for a gendered dimension in the development of policy and practice for HIV and AIDS prevention.
The needs of people with Parkinson's disease (PD) go beyond the purely medical domain and often require collaborative management. A Panel Discussion at the "Hither neurology" Symposium included neurologists, a speech therapist, a geriatrician and a sociologist. Their discussion highlighted certain aspects of the disability and disadvantage associated with PD. The starting point was a video recording, "Parkinson's Disease: the personal view", in which the contributors were patients and carers. Topics covered included counselling at the time of diagnosis; subsequent access to clinics and to neurological advice; access to therapy; support in the community; fluctuating disability associated with "on-off" phenomena; driving; and sexual problems.
BACKGROUND: The aim was to develop a standardised and externally paced field walking test, incorporating an incremental and progressive structure, to assess functional capacity in patients with chronic airways obstruction. METHODS: The usefulness of two different shuttle walking test protocols was examined in two separate groups of patients. The initial 10 level protocol (group A, n = 10) and a subsequent, modified, 12 level protocol (group B, n = 10) differed in the number of increments and in the speeds of walking. Patients performed three shuttle walking tests one week apart. Then the performance of patients (group C, n = 15) in the six minute walking test was compared with that in the second (modified) shuttle walking test protocol. Heart rate was recorded during all the exercise tests with a short range telemetry device. RESULTS: The 12 level modified protocol provided a measure of functional capacity in patients with a wide range of disability and was reproducible after just one practice walk; the mean difference between trial 2 v 3 was -2.0 (95% CI -21.9 to 17.9) m. There was a significant relation between the distance walked in the six minute walking test and the shuttle walking test (rho = 0.68) but the six minute walking test appeared to overestimate the extent of disability in some patients. The shuttle test provoked a graded cardiovascular response not evident in the six minute test. Moreover, the maximal heart rates attained were significantly higher for the shuttle walking test than for the six minute test. CONCLUSIONS: The shuttle walking test constitutes a standardised incremental field walking test that provokes a symptom limited maximal performance. It provides an objective measurement of disability and allows direct comparison of patients' performance.
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This study evaluated the use of new small transvenous atrial and ventricular leads for converting atrial fibrillation (AF) and ventricular fibrillation (VF) in 10 adult male mongrel dogs. Five dogs (group A) received a right atrial "J" (AJ) and right ventricular (RV) active fixation tripolar lead, each consisting of a platinized platinum pacing tip, anode band, and braided defibrillation electrode. The remaining five dogs (group B) received one bipolar RV lead and one tripolar AJ lead. The RV leads were implanted in the right ventricular apex (RVA) and the AJ leads were placed in the atrial appendage. Additionally all dogs received two 8 French subcutaneous defibrillation catheters in the fifth and seventh intercostal spaces. Twenty asymmetric biphasic shocks consisting of five randomized voltage levels were used to convert VF in groups A and B. The bipolar RV lead (group B) had a significantly higher probability of success in converting VF than the tripolar RV lead (group A). In group A defibrillation thresholds for converting AF were obtained using two electrode configurations. No significant difference was observed between the two electrode configurations used to convert AF. Pacing and sensing thresholds were satisfactory for bipolar and tripolar lead configuration.
This report describes a salvage pathway whereby activated T lymphocytes revert to nonproliferating cells in the absence of antigen or mitogenic signals. After the removal of mitogenic cytokines, cultured T lymphocytes cease dividing and rapidly begin to undergo cell death. However, the addition of fibroblasts to interleukin 2 (IL-2)-propagated T cells results in prolonged survival of the previously activated T lymphocytes in the absence of proliferation. The prevention of cell death is also achieved by conditioned medium from the fibroblasts. T lymphocytes cultured with fibroblasts or the conditioned medium retain the ability to be restimulated if mitogenic stimuli are added to the culture. The activity is not accounted for by IL-1-7. The studies suggest a stromal cell-mediated, nonspecific mechanism for survival of primed T lymphocytes in a nonproliferating state.
Blood transfusion in the perioperative period has been reported to have a detrimental effect on survival in many types of cancer. Other studies have failed to confirm this. We have examined retrospectively the records of 246 patients with prostatic carcinoma who underwent transurethral resection of the prostate (TURP) in Aberdeen Royal Infirmary between 1977 and 1982. Bilateral orchiectomy (BLO) was performed in 193 patients. Of these patients, 71 of 246 (29 per cent) received perioperative blood transfusion. After controlling for differences due to a number of variables, transfusion of non-autologous blood was shown to be associated with a significant negative effect on survival. Perioperative transfusion of non-autologous blood should be avoided in patients with malignancy, unless there are clear overriding clinical indications. Prospective trials are needed urgently.
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We have studied the association of muscle strength (quadriceps, biceps, handgrip), measured by a portable chair technique, with functional status (Barthel Index, manual dexterity, Mental Test Score, history of falls, fracture, prescribed drugs), in a sample of 92 elderly subjects attending a Local Authority Day Centre and Day Hospital. Anthropometric measurements and hand-grip strength were also measured in 30 young controls. Muscle area, mass and strength were significantly greater in young controls. Elderly men had significantly greater muscle area, mass and strength than elderly women. Muscle strength correlated with several measures of functional status. Using stepwise multiple regression, an independent association of muscle strength with manual dexterity, Barthel Index and receipt of domiciliary services is demonstrated.
Periodic stimuli such as sine-wave gratings and checkerboard patterns have been used in many studies of visual perception. It is well known that with such stimuli, visual persistence increases as spatial frequency increases and as contrast decreases. It is not clear, however, that similar relationships obtain for aperiodic stimuli such as natural images. Digitized images of objects (a face and a vase) were submitted to two-dimensional Fourier analysis. Four pairs of spatial frequency band-limited images were created for each image. Each pair consisted of a normal (NP) and a scrambled (SP) phase version, with the magnitude spectrum and space-averaged luminance the same within each pair. Filter bandwidths were one octave wide. Threshold persistence was measured for each spatially filtered image. Visual persistence for SP images increased significantly as spatial frequency increased, whereas no significant differences were found for NP images. This suggests that the temporal processing of complex, aperiodic visual images is influenced by the spatial frequency and contrast of local features within the image and cannot be predicted by space-averaged estimates of contrast and spatial frequency.
This article has been written jointly by Ingried Morris, a dentist, and Sheila Scott, a marketing consultant. Ingried discusses some of the reasons why her colleagues may reject the marketing approach to dentistry, while Sheila argues that many of these skepticisms are indeed good reasons to embrace the discipline wholeheartedly. We felt that the article posed many questions, often unspoken, that worry a number of the profession who find it difficult harmonizing their perception of a commercial technique--marketing--with treating their patients in a caring profession. The article then goes on to answer those questions and suggests that true marketing is indeed caring, and can only strengthen the quality of clinical care.