PubMed Health⌕ Search

Biomedical subjects

S Seeberg

Publications and source records attributed to S Seeberg.

At least 37 records · Page 2Linked to original sources
PubMed1980

Septicaemia in patients with central vein catheters. An evaluation of a method including weekly exchange of catheter.

A method for the care of central vein catheters (CVC) including exchange of catheter is described. The method has been used during 6 years in an intensive care unit for patients with severe infections. Nine out of 140 patients (6%) developed catheter related septicemia which was considered as a satisfactory result for patients with plre-existing systemic infection. A bacteriological study showed that the puncture site was colonized by bacteria belonging to the skin flora one day after introduction of a CVC. Cultures from the catheter tip mainly seemed to reflect the flora at the puncture site.

Adolescent↗
PubMed1979

A bacteriological evaluation of a programme for preoperative total body-washing with chlorhexidine gluconate performed by patients undergoing orthopaedic surgery.

Twenty-eight orthopaedic patients were taught to wash their entire bodies with chlorhexidine gluconate on two consecutive days preoperatively, starting in their homes. The operation field was also washed a third time. A bacteriological evaluation was performed using contact plates. A significant reduction of the skin flora, including Staph. aureus, was registered. No adverse side effects of total body-washing were observed.

Bacterial Infections↗
PubMed1976

Comparative study of the in vitro antibacterial activity of cefoxitin, cefuroxine, and cephaloridine.

The in vitro antibacterial effects of cefoxitin, a semisynthetic cephamycin, cefuroxime, a new cephalosporin antibiotic, and cephaloridine were compared. With gram-positive bacteria, marked differences were found only in the effects against Streptococcus faecalis, where cephaloridine and cefuroxime were superior to cefoxitin. With gram-negative aerobic bacteria, cefoxitin, which is known to be more resistant to beta-lactamases from gram-negative bacteria than any cephalosporin, was found to be more effective than cefuroxime and cephaloridine against ampicillin-resistant strains of Escherichia coli and indole-positive strains of Proteus. Haemophilus influenzae was found to be more susceptible to cefuroxime than to cefoxitin and cephaloridine. When ampicillin-resistant strains of H. influenzae were tested, markedly higher minimal inhibitory concentration values were obtained with cephaloridine in comparison to those obtained with ampicillin-susceptible strains. These increases in the minimal inhibitory concentration values were not observed with cefoxitin and cefuroxime, probably due to the resistance of these two compounds to beta-lactamases. Strains of Bacteroides fragilis were found to be much more susceptible to cefoxitin than to cefuroxime, which in turn was superior to cephaloridine. The results obtained indicate that cefoxitin and cefuroxime both are superior in their antibacterial spectra to the cephalosporins that are now in clinical use.

Bacteria↗
PubMed1975

Properties of some staphylococcus aureus strains associated with spontaneous l-phase transformation.

Spontaneous L-phase production was found in 7 of 14 investigated Staphylococcus aureus strains. A common characteristic of the strains producing L-phase variants spontaneously was their ability to develop L-colonies on a solid medium with 1.0-1.5% NaCl by the action of methicillin, whereas other strains required higher NaCl concentrations. Further, in 6 of the 7 strains the ability for spontaneous L-phase production was associated with high L-phase productivity in the presence of methicillin. The pattern of alpha-, beta- and delta-hemolysin production in a strain was not correlated to spontaneous L-phase production.

Hemolysin Proteins↗
PubMed1975

Meningitis developing during cephalothin therapy of septicaemia.

A 63-year-old woman developed pneumococcal meningitis during cephalothin treatment for pneumococcal septicaemia. The poor penetration of this antibiotic over the blood-brain barrier makes it unsuitable for the therapy of meningitis. If cephalothin is used in other serious infections, the patient should be closely observed for the development of meningitis.

Blood-Brain Barrier↗
PubMed1975

Prolonged survival of non-multiplying Staphylococcus aureus cells undergoing autolysis in the presence of certain inhibitors of cell wall synthesis.

Certain antibiotic compounds including penicillin, cloxacillin and 6-APA caused a prolonged survival of Staph. aureus cells undergoing autolysis in physiologic saline. The retardation of the death rate was dependent upon the type of compound and its concentration. The results suggest that the compounds inhibit the autolytic function of the bacteria.

Autolysis↗
PubMed1975

Effect of consecutive antibacterial therapy on bacteriuria in hospitalized geriatric patients.

The effects of treatment with a consecutive series of different antibacterial drugs, most of them commonly used in urinary tract infections, were studied in 36 hospitalized geriatric patients with bacteriuria. Most of the patients had advanced handicaps and all had urinary incontinence. Urinary acidifying drugs, penicillin V, sulfonamide, nitrofurantoin, nalidixic acid, and trimethoprim/sulfamethoxazole were used as antibacterial agents. The general conclusion was that even the administration of a series of potent antibacterial drugs only rather seldom eliminates bacteriuria in such patients, and that the original bacteria in most cases are replaced by strains highly resistant to antibacterial drugs. The treatment had obvious influence on the clinical state only in one patient.

Age Factors↗