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Biomedical subjects

S Sendler

Publications and source records attributed to S Sendler.

3 recordsLinked to original sources

[Artificial divergence surgery in congenital nystagmus].

The treatment possibilities for nystagmus have been expanded by the addition of the artificial divergence procedure. This paper presents a study on 26 nystagmus patients with and without anomalous head posture and good binocular function and with detailed pre- and postoperative electronystagmographic records. All patients had been treated by artificial divergence by means of a prism base out before the operation. Seventeen patients showed significant improvement after the artificial divergence procedure. In 3 patients this procedure had to be combined with the classic Kestenbaum procedure. In 6 patients, the effect of artificial divergence with prisms was not satisfactory; thus, the Kestenbaum procedure was necessary. This study proves the effectiveness of the artificial divergence procedure alone or in combination with other procedures for treatment of anomalous head posture and the improvement of visual acuity and binocular vision.

Adolescent

Does Bowman's layer determine the biomechanical properties of the cornea?

BACKGROUND: Bowman's layer is believed to be the stabilizing element of corneal curvature due to its assumed mechanical stiffness. METHODS: Uniaxial stress-strain analysis was performed in paired corneal strips to compare the contribution from Bowman's layer. Two central strips were taken from each cornea and Bowman's layer was removed from one of them with the excimer laser. RESULTS: Pairwise comparison yielded no statistical difference in elastic or viscoelastic properties according to presence or absence of Bowman's layer. At a strain of 2%, the stress was measured to be (5.06 +/- 2.01) x 10(3) N/m2 with Bowman's layer and (4.72 +/- 1.3) x 10(3) N/m2 without Bowman's layer. Also, the two relaxation times did not differ significantly. CONCLUSIONS: These findings imply that Bowman's layer does not contribute significantly to mechanical stability within the cornea.

Aged

Cell seeding on microporous and solid polyurethane.

Cell coating with human embryonal fibroblasts was examined on solid (Plathurane UM 8300) and microporous (Tecoflex 80 A) polyurethane. Using measurements of cellular growth kinetics and adhesion strength it was found that the onset of cellular growth on the microporous material was delayed but that the vitality and adhesion strength of the cells were better than for the solid material.

Cell Adhesion