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Biomedical subjects

S Sentürk

Publications and source records attributed to S Sentürk.

8 recordsLinked to original sources
PubMed2006

Urinary tract infections due to Mycoplasma canis in dogs.

Urine samples were obtained from 100 dogs with symptoms of lower urinary tract disease by cystocentesis and were examined for mycoplasmas. Urinalysis, haematological and biochemical analyses were also performed. Bacteria were isolated from urine in 41 of 100 dogs; Mycoplasma canis was isolated from four of 100 (4%) urine samples and three were pure culture. Selective mycoplasma media were used for isolation. In growth inhibition test, propagation of the four M. canis isolates was inhibited by their specific hyperimmune sera and there was no cross reactivity between isolates and hyperimmune sera of other mycoplasmas. Dogs in which M. canis was isolated were azotemic. All dogs were treated with enrofloxacin, furosemide, and supportive therapy (fluid therapy, ascorbic acid). In all animals, clinical improvements were observed after treatment.

Animals↗
PubMed2005

Evaluation of the anti-endotoxic effects of polymyxin-E (colistin) in dogs with naturally occurred endotoxic shock.

Endotoxin is a potent stimulator of the inflammatory response and is believed to initiate the pathology in gram-negative sepsis. Agents are being searched for that bind and neutralize or block the effects of endotoxin. The aim was to study the anti-endotoxic effects of polymyxin-E (colistin) in endotoxaemic dogs. The study included a total of 30 endotoxaemic dogs, which were divided into two groups (control = 15; test = 15) of both sexes, different breeds and ages. Hetastarch colloid solution (Expahes,10 mL/kg, i.v.) with lactated Ringer's solution (20 mL/kg, i.v., Q12 h) was given to all dogs. While ampicillin was administered (Alfasilin, 10 mg/kg, i.m., Q12 h) as an antibacterial to the control group, colistin (12,500 IU/kg, i.m., Q12 h) + ampicillin were administered to the test group. The clinical examination (body temperature, pulse and respiration rates, capillary filling times, peripheral pulse qualities, dehydration degrees), hematological and biochemical examinations (WBC, RBC, HGB, HCT, thrombocyte, serum urea, creatinine and TNF-alpha) were performed both before the treatment, and 2, 4, 12 and 24 h after the treatment. In comparison with the control group, it was observed that test group had shorter capillary filling time at 24 h (P < 0.001). Moreover, the degree of dehydration in test group, was significantly improved at 24 h (P < 0.01). While the differences in peripheral pulse qualities significantly differed between 0 and 2 h in controls, at 2, 4, 24 h after treatment it was found to be significantly increased when compared with 0 h in the test group. Serum TNF-alpha concentrations were statistically decreased in the test group between 0 h and other times (P < 0.01). When compared with controls, serum TNF-alpha concentrations were lower at 2, 4, 12 and 24 h in test group (P < 0.05). Results of the study indicated that polymyxin-E (colistin) has an anti-endotoxic effect and is safe for the dogs with endotoxemia at the dosage used in this study.

Ampicillin↗
PubMed2003

Hypocholesterolaemia in dogs with dominance aggression.

Serum lipids and lipoprotein concentrations have been associated with dominance aggression in humans. The aim of this study was to investigate the link between serum lipids, including cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC) to HDL-C ratio and dominance aggression in dogs. Levels of serum TC, triglyceride and HDL-C were significantly lower in dogs with dominance aggression compared with non-aggressive dogs (P < 0.001). These results suggest that a relationship exists between serum lipid profile and dominance aggression in dogs, and hypocholesterolaemia exists in dogs with dominance aggression.

Aggression↗
PubMed2003

Effects of a hypertonic saline solution and dextran 70 combination in the treatment of diarrhoeic dehydrated calves.

Thirty dehydrated diarrheic calves aged 2-45 days were used to study the effects of small volume intravenous 7.2% hypertonic saline and 6% dextran 70 solution in combination with alkalinising oral fluids and to compare this therapy with the large volume intravenous isotonic saline with alkalinising oral fluid treatment. This study included a total of 30 diarrhoeic dehydrated calves aged 2-45 days. After routine clinical and haematological examinations, the calves were allotted to two treatment groups. Isotonic saline solution (32 ml/kg, i.v.) with an oral electrolyte solution (22 ml/kg, p.o.) were administered to group I (control), and the combination of 7.2% hypertonic saline in 6% dextran 70 solutions (HSD) (4 ml/kg, i.v.) with an oral electrolyte solution (50 ml/kg, p.o.) were administered to group II (test). Additionally, an oral electrolyte solution (50 ml/kg, p.o.) was readministered to both groups at 12 h of the study. The clinical and haematological examinations of all calves were performed both before and after the treatment at the 1/2, 1, 2, 4, 12 and 24 h. The capillary refill time, peripheral pulse quality, dehydration degrees, mental status, haematocrit rates, haemoglobin and plasma values after treatment were found to be statistically different compared with the values before treatment. In comparison with group I, group II is observed to have shorter capillary refill time at 1, 4 and 12 h (P < 0.001) and better peripheral pulse quality at 1/2 (P < 0.05), 1, 2, 4 and 12 h (P < 0.001). Moreover, the degree of dehydration in group II, was significantly improved at 2 (P < 0.01), 4 and 12 h. Results of the study indicated that administration of low volumes of hypertonic sodium chloride and dextran 70 solution combinations with oral electrolyte solutions was concluded as quicker, practical, economical and most importantly an effective way for the treatment of dehydrated diarrhoeic calves.

Administration, Oral↗