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Biomedical subjects

S Sermasi

Publications and source records attributed to S Sermasi.

13 recordsLinked to original sources

Automatic external defibrillators in the hospital as well?

When a cardiac arrest occurs in a non-intensive area of the hospital, the emergency response is not always adequate from the point of view of timeliness and technical quality. The aims of this study were evaluate an experimental programme to improve the CPR skills of staff operating in non-intensive areas of our general hospital and to test the usefulness of placing automatic external defibrillators (AEDs) within these areas. In the experimental phase, two AEDs were placed in 2 non-intensive wards of our hospital for 8 months. The staff of these wards received specific training in CPR and early defibrillation (CPR-D). The devices were used in 19 cases; for defibrillation in four cases of ventricular fibrillation (VF) (three patients were discharged alive from hospital), and for monitoring three supraventricular arrhythmias, one bradyarrhythmia and 11 cardiac rhythms during critical situations. In the implementation phase, four AEDs were indefinitely assigned to as many non-intensive awards. Periodical CPR-D courses and refresher exercises were run; the cardiology staff co-operated in the maintenance of the AEDs and in the registration of technical and clinical data. In the first period of this phase (9 months), AEDs were utilized in 24 cases by the ward-staff: in nine cases for VF (three patients were discharged alive from hospital) and in 15 cases for other rhythm detection in critical conditions. The number and the quality of these uses seem to confirm the favourable impact of the adoption of a more user-friendly defibrillator, such as an AED. The active co-operation between intensive and non-intensive staff was important to facilitate a quick activation of the chain of survival outside the intensive care units. We conclude that AEDs, which were developed for out-of-hospital use by non-physician operators, are suitable for use inside the hospital as well.

Adult

[Elective electric cardioversion of atrial fibrillation in adults with underlying heart disease: a proposal of optimizing the procedure].

BACKGROUND: Synchronized direct current cardioversion (DC) is widely used for atrial fibrillation (AF) conversion to sinus rhythm. With the purpose to identificate the optimal procedure for the effective DC of AF, we compared the results obtained following traditional free-multiple shock sequence to simple two-shock sequence in two groups of adults with underlying heart disease submitted to elective DC for AF in our Dept. of Cardiology. METHODS: The first group, retrospectively considered, included 84 episodes of AF occurred in 79 patients. DC started on an energy level of 100 joules (J) and, when unsuccessful, repeated on increasing levels, from 150J to 360J, depending on physician preference. An additional shock of 360J was always delivered when the last shock-dose proved to be ineffective. The second group, prospectively considered, included 61 episodes of AF occurred in 61 patients. The protocol provided for an initial shock of 200J followed, when necessary, by a second one of 360J and no additional shocks. RESULTS: Conversion rate (86.9% vs. 85.2%) showed no statistical difference (p = NS) between groups. Following the two-shock protocol, a significant reduction of the mean amount of energy used for effective conversion (258.5J vs. 345.0J; p < 0.001), of the mean amount of total energy delivered to patients (302.9J vs. 439.6J; p < 0.001), particularly to non responders (560.0J vs. 1067.2J; p < 0.0001) was found. Using the first procedure only 13.1% of patients were cardioverted delivering 100J and 35.8% of them needed additional 200J. In the second group, the initial shock of 200J cardioverted 54.1% of patients. In both studies no patients had adverse effects either during or early after DC or during the four-week follow-up, where haemorrhagic and thromboembolic complications has been also considered. CONCLUSIONS: Two-shock protocol seems to provide better success/total energy delivered ratio, to reduce the total amount of energy delivered to each patient and to shorten the DC procedure when compared to free-multiple shock sequence usually performed, reducing the total time of anesthesia.

Adult

[Non-invasive conversion of atrial flutter using an implanted double-chamber pacemaker].

The increasing sophistication of implantable pacemakers for treating both tachycardia and bradycardia has resulted in the ability to use the implanted device for more interventions other than simple pacing. The interruption of tachyarrhythmias has been attempted using special programmers which allow stimulation at different cycle lengths, even very short ones. We describe two cases in which neither antitachycardia device nor special equipment were used to terminate an atrial flutter. Two patients with Sick Sinus syndrome who had received DDD pacemaker, presented with a sustained atrial flutter. Pacers were set in AOO mode at the highest rate programmable (119 and 130 ppm, respectively) obtaining an underdrive atrial pacing (F-F rate was 280 ppm in both cases) which was able to convert the atrial flutter to sinus rhythm. The procedure was performed in the outpatient clinic. Our cases illustrate one of many potential applications of permanent pacemakers in noninvasive settings. We can conclude that when atrial flutter occurs in AAI or DDD pacemaker recipients, underdrive atrial pacing using the implanted pacemaker should always be attempted.

Aged

VDD single pass lead pacing: sustained pacemaker mediated tachycardias unrelated to retrograde atrial activation.

Pacemaker mediated tachycardias (PMTs) are a well known complication of P synchronous pacing. Although the initiating mechanisms are several, all of them are associated with retrograde atrial activation, which is sensed by the atrial sensing channel, resulting in ventricular pacing. In 19 patients suffering from symptomatic AV conduction disturbances and normal sinus node function, a VDD pacing system connected to a single pass ventricular lead with dual chamber electrodes was implanted. The bipolar atrial electrode, floating in the right atrium, was used to detect endocardial atrial electrograms that were differentially processed within the pacemaker for optimal discrimination and filtering of undesirable signals. The widely programmable atrial sensitivity (amplitude and filtering) allowed stable P synchronized ventricular pacing in all patients, but in five of them, sustained PMTs not related to retrograde atrial activation was documented during the follow-up. The common mechanism for the onset and maintenance of these PMTs was traced to the abnormal sensing of the terminal forces of ventricular activation and/or of the T wave. The possibility of interferences between ventricular and atrial electrodes (crosstalk) was also considered. The reduction of atrial channel sensitivity represented in all cases the only effective procedure to prevent this type of PMT. In conclusion, the bet signal to noise ratio is an important endpoint to assure the proper function of a single lead VDD pacing system. Furthermore, using the differential amplifier built within the pacemaker, consideration should be given to the optimal mode of rejection of the terminal forces of the QRS and T wave.

Aged

[Accidental ventricular fibrillation during transesophageal atrial overdrive].

Transesophageal atrial overdrive stimulation is a widely used technique for the interruption of atrial flutter and supraventricular tachyarrhythmias. We describe a case of 60 year old man with a previous myocardial infarction, suffering from angina during effort after aortocoronary bypass who presented several episodes of atrial flutter treated with success by transesophageal atrial overdrive stimulation using swallowing electrodes. During the treatment of the last episode of atrial flutter, after a 5 s burst at 300 b/min ventricular fibrillation occurred and was promptly interrupted by DC shock. This is the first case in our experience and probably the first report of ventricular fibrillation induced by swallowing electrodes. Possible mechanisms as pharmacological interactions, accidental ventricular stimulation, etc, are discussed. In conclusion, even though the risk of dangerous arrhythmias is very low, transesophageal atrial overdrive stimulation should be performed by experts in an equipped room.

Angina Pectoris

Usefulness of 1-hour and 24-hour heart rate Holter inbuilt in new TX* rate adaptive pacemakers.

The rate adaptive TX* pacemaker uses the evoked QT interval as an indicator of physiological demand. In order to obtain a rate adaptation close to physiological patterns we used in the past, in each patient, on the slope value and/or the T wave sensing window, controlling via exercise stress testing and Holter the results achieved. It was an expensive method, but the system produced effective rate responsive pacing. The new series of TX* pacemakers (Quintech 919 and Rhythmyx), beside the dynamic slope feature, are equipped with a 1-hour heart rate Holter (HRH) that can be used during effort without the need for manually recording the heart rate. In this mode TX* pacemakers calculate the average heart rate over 20-second periods and stores the values continuously for 1 hour. In addition, a 24-hour HRH is available, which calculates the average heart rate over 7.5-minute periods, showing heart rate trend during the last day prior to interrogation. Each HRH can be accessed by the programmer and printed out. Using four Quintech 919* and five Rhythmyx units, the inbuilt HRH proved its utility by making the heart rate adaptation checking procedure easier, faster, and more economic.

Atrial Fibrillation

[The left posterior fascicular block: is the diagnosis possible only by ECG? (author's transl)].

The diagnosis of Left Posterior Fascicular Block based on clinical ECG and VCG tracings alone is possible when ECG and VCG allow to recognize asynchronous left ventricular activation. The delayed inscription time of the intrinsecoid deflection in aVF (or V6) in absolute and relative to aVL permits the diagnosis if intrinsecond deflection in aVL exceeds 0,035". Il more premature, a further control is required to distinguish Left Ventricular Hypertrophy from Left Posterior Fascicular Block, both in anatomically vertical heart.

Electrocardiography

[Lidocaine administration in a patient with Wolff-Parkinson-White syndrome and atrial fibrillation (author's transl)].

This report describes a case of Wolff-Parkinson-White syndrome with atrial fibrillation in which the ventricular complexes conducted over the accessory pathway have promptly disappeared with the use of intravenously administered lidocaine. Lidocaine is suggested as the most suitable drug in such situations. Finally possible connections are presented between high dosage administered lidocaine and conversion to normal sinus rhythm.

Atrial Fibrillation