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Biomedical subjects

S Setzer

Publications and source records attributed to S Setzer.

13 recordsLinked to original sources
PubMed2004

Pulpitis induction in baboon primary teeth using carious dentine or Streptococcus mutans.

The objective of this equivalency study was to see if a colony of Streptococcus mutans placed into cavities in primary molar teeth produced pulpitis similar to an established pulpitis induction method using carious dentine. In two juvenile baboons (Papio ursinus), occlusal cavities were cut in all 16 primary molar teeth, followed by making a small pulpal exposure after which the cavity was swabbed with 37 per cent phosphoric acid. In one half of the teeth, fresh soft human carious dentine was placed over the pulpal exposure; in the remaining teeth the exposure was covered with a colony of Streptococcus mutans in agar. All the cavities were restored with unlined light-cured composite resin. After 14 days specimens were harvested and examined under the light microscope with the examiner blind to the induction method. In both groups of teeth there was recognisable pulp, hyperaemia, micro-abscesses in the pulp and peri-apical abscesses. Reactions to soft caries were more severe than to Streptococcus mutans. The results show that Streptococcus mutans placed in a cavity with an exposure produces comparable pulpitis to fresh soft human carious dentine in the same type of cavity and that both methods produce pulpitis suitable for testing pulpotomy or pulpectomy treatments.

Abscess↗
PubMed2004

Zinc oxide-eugenol and calcium hydroxide pulpectomies in baboon primary molars: histological responses.

AIM: To compare histological responses to zinc oxide-eugenol (ZOE) and calcium hydroxide (CH) pulpectomies in primary molar teeth with inflamed pulps. STUDY DESIGN: This was an experimental study in 17 juvenile baboons (Papio ursinus). METHODS: Pulpitis was induced with fresh human carious dentine or Streptococcus mutans placed into occlusal cavities in 78 primary molars; after 14 days a pulpectomy was performed on the same primary molars with the two root fillings randomly allocated. The root canal openings were then covered with IRM and the cavity filled with amalgam. After 90 days specimens were harvested and examined under the light microscope with the examiner blind to the treatment. RESULTS: Reaction frequencies in the ZOE-treated versus CH-treated teeth were: no recognisable pulp 89% and 82%, internal root resorption 0% and 1%, external root resorption 11% and 24%, presence of bacteria 5% and 18%, periapical abscesses 24% and 52%. STATISTICS: Fisher's exact probability test showed a statistically significant higher prevalence of periapical abscesses in the CH-treated group (P=0.03, relative risk 2.2). CONCLUSIONS: ZOE pulpectomy is preferred to CH for the treatment of infected pulps in primary molars.

Animals↗
PubMed2002

Generation of GW radiation pulses from a VUV free-electron laser operating in the femtosecond regime.

Experimental results are presented from vacuum-ultraviolet free-electron laser (FEL) operating in the self-amplified spontaneous emission (SASE) mode. The generation of ultrashort radiation pulses became possible due to specific tailoring of the bunch charge distribution. A complete characterization of the linear and nonlinear modes of the SASE FEL operation was performed. At saturation the FEL produces ultrashort pulses (30-100 fs FWHM) with a peak radiation power in the GW level and with full transverse coherence. The wavelength was tuned in the range of 95-105 nm.

Journal Article↗
PubMed2001

Bonding agents: adhesive layer thickness and retention to cavity surfaces with time.

This study assessed bonding agent thickness, cover and the influence of long-term storage on bonding agent retention to enamel and dentine surfaces in cut occlusal cavities in 46 human molar teeth. Two specimens were etched and set aside. The remaining specimens were divided into two equal groups and treated with either Optibond or Scotchbond Multipurpose Plus (SMPP) up to the adhesive stage. Thereafter two specimens from each group were stored for 0, 1, 3, 7 and 14 days and 1, 2, 3, 6 and 12 months in 1% NaCl. After storage the cavity surfaces were examined in a scanning electron microscope (SEM) and scored as to bonding agent cover. One specimen from each treatment was then embedded in resin, two sections prepared midway through each cavity, polished and re-examined in the SEM to measure bonding agent thickness at 13 sites along the cavity surface. Both bonding agents showed highly variable and significant (P < 0.05) bonding agent cover and layer thickness according to cavity site, SMPP more so than Optibond. Pooling of SMPP adhesive was apparent in cavity angles. Mean film thickness was significantly different between Optibond (221 +/- 130 microns) and SMPP (118 +/- 106 microns). There was no significant difference in bonding agent thickness between long- and short-term storage.

Analysis of Variance↗
PubMed2001

How does zinc oxide-eugenol compare to ferric sulphate as a pulpotomy material?

This study compared the clinical and radiographic responses after 3 months to a sterile compression technique with zinc oxide-eugenol or 15.5% ferric sulphate in 145 pulpotomised primary teeth in 30 children. In both groups of teeth the success rate was 100%. These short-term results suggest that either technique may be used.

Child↗
PubMed2000

First observation of self-amplified spontaneous emission in a free-electron laser at 109 nm wavelength

We present the first observation of self-amplified spontaneous emission (SASE) in a free-electron laser (FEL) in the vacuum ultraviolet regime at 109 nm wavelength (11 eV). The observed free-electron laser gain (approximately 3000) and the radiation characteristics, such as dependency on bunch charge, angular distribution, spectral width, and intensity fluctuations, are all consistent with the present models for SASE FELs.

Journal Article↗
PubMed1999

Comparison of a short examination procedure with an extensive diagnostic protocol for the diagnosis of temporomandibular disorders.

Eighty-nine patients who complained of temporomandibular disorders were examined using a short and long examination procedure. Seventy were females and 19 males. Mean age of the group was 31.53 years, with a range from 11 to 73 years. The agreement between the two examination procedures was tested using the Kappa statistic. This gave a value of 0.876 (P<0.001). This allowed rejection of the hypothesis that the agreement found between the two procedures was due to chance alone.

Adolescent↗
PubMed1997

Shear bond strength of amalgam and gallium alloys to dentine.

The purpose of this in vitro investigation was to determine the shear bond strength of admixed (Dispersalloy), irregular (Oralloy) and spherical (Lojic) amalgams, as well as an admixed gallium alloy (Galloy) to superficial, buccal, human dentine surfaces, using the Scotchbond Multi-Purpose Plus system. The bonds were stressed to failure in an Instron testing machine after 48 hours, and the following values (MPa) were obtained: Admixed = 7.74 +/- 0.7; Irregular = 9.47 +/- 1.4; Spherical = 9.82 +/- 2.4; Galloy = 11.03 +/- 2.5. Data were statistically analysed and fracture sites examined in a scanning electron microscope. Galloy demonstrated a statistical significant higher shear bond strength than to the other types of amalgams (p < 0.01).

Dental Alloys↗
PubMed1991

Elevated 25-hydroxy and normal 1,25-dihydroxy cholecalciferol serum concentrations in a successfully-treated case of vitamin D3 toxicosis in a dog.

A 4-y old, 27 kg spayed female German Shepherd dog was observed to ingest one 1-oz package of a rodenticide containing cholecalciferol. An initial serum calcium concentration of 15.7 mg/dl was successfully reduced to normal during 10 d using calcitonin and prednisolone. During that time, the serum 25-hydroxy and 1,25-dihydroxy cholecalciferol concentrations ranged from 637 to 315 ng/ml (normal 32 +/- 6 ng/ml) and 64 to 29 pg/ml (normal 34 +/- 19 pg/ml), respectively. Serum mid-molecule parathyroid hormone concentrations (76 to 97 pcmol/L) were within the normal range (85-140 pcmol/L). These data indicate that hypercalcemia seen in dogs following field exposures to cholecalciferol-containing rodenticides may be associated with elevated 25-hydroxy rather than 1,25-dihydroxy cholecalciferol. Consequently, serum 25-hydroxy cholecalciferol concentrations may be the most conclusive method for diagnosing hypervitaminosis D3 toxicosis in the live dog.

Animals↗
PubMed1989

Teaching models for Nd:YAG laser bronchoscopy.

A number of groups have demonstrated the efficacy of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser bronchoscopy for treatment of patients with selected tracheobronchial disorders. This therapy involves a new technology, the laser, and new adaptations of conventional rigid and flexible bronchoscopy that are unfamiliar to many bronchoscopists. We describe two teaching models for laser bronchoscopy that have been employed successfully in our laser courses. Using these models, bronchoscopists can become familiar with laser bronchoscopic equipment and appreciate the interaction of laser and soft tissue in a controlled setting in the laboratory before applying this therapy to patients.

Animals↗
PubMed1983

Primary dentition caries trends, 1976-1981, in four South African populations.

This paper is a comparison of cross-sectional data on dental caries in the primary dentition undertaken between 1976 and 1981 in the Transvaal Province, South Africa, on 690 rural Black, 1463 urban Black, 870 Indian and 1622 White children aged 2-5 yr. There was a decrease in percentage dental caries prevalence in the urban White children and an increase in the other three groups, the fastest rate being seen among urban Indian children. Similar trends were noted for mean dmft. Dental caries in incisor and canine teeth remained fairly static but caries in molar teeth increased in the groups of Black and Indian children and decreased in the White children. Ratios d/dmft, m/dmft and f/dmft indicated that minimal treatment was received by all the children.

Black People↗