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Biomedical subjects

S Shashidhar

Publications and source records attributed to S Shashidhar.

8 recordsLinked to original sources
PubMed2001

Pulmonary functions in workers of fertiliser and chemical industry.

The present study was undertaken to assess the pulmonary functions in fertiliser and chemical industry workers of Kerala. Pulmonary function test was performed with Vitalograph Compact-II spirometer. Exposure to different chemicals, noxious gases and particulate matter of fertiliser and chemical industry was injurious to the normal pulmonary function. Significant decline in lung volumes, viz. FVC, FEV1, FEV1/FVC% (P < 0.01) and flow rates, viz. FEF25-75%, FEF0.2-1.2, FEF25%, FEF50%, FEF75% (P < 0.01) among non-smokers and smokers than that of normal controls was observed. The findings of this study also suggest that with increased duration of exposure to industrial pollutants, lung volumes and flow rates were significantly reduced in workers.

Chemical Industry↗
PubMed2001

Lipid peroxidation and diabetic retinopathy.

The high level of glucose in blood for a long duration is the main cause of the development of retinopathy. So yearly screening of patients newly diagnosed with NIDDM diabetes is recommended because rare cases of treatable diabetic retinopathy have occurred early in one course of NIDDM diabetes. Hyperglycaemia leads to non-enzymatic glycosylation of proteins and HbA1C was found increased. Antioxidants such as GSH and SOD level is found decreased in retinopathy conditions due to the higher lipid peroxidation, which is evident from high MDA and DC values. So it can be clearly stated that increase in the free radical by hyperglycaemia, lipid peroxidation and advanced glycosylation endproducts along with decreased antioxidants are the causative agents for the development of retinopathy.

Diabetes Mellitus, Type 2↗
PubMed2001

Lung volumes in swimmers performing different styles of swimming.

The alteration of lung volumes in swimmers performing different strokes was the theme of the present study. The study was carried out due to lack of knowledge regarding the lung volumes of different strokers. As the energy expenditure, O2 consumption rate, body movements, viz. arm and leg movements differ with each stroke, the lung function status and mechanics of breathing in swimmers has to cope up with the stroke techniques. Lung volumes, viz. VC, FVC, FEV1 and RVind decrease from resting condition to after swimming performance in freestyle swimmers and butterfly stroke swimmers. The primary reason for the decline in lung volumes after exercise bout, found out from several reports is that it may be due to the fatigue of respiratory muscle. When lung volumes of different swimming strokers were compared with age and height matched controls a higher lung volume were observed in swimmers performing different strokes. Higher breath holding ability of swimmers may facilitate the increase in the strength of respiratory musculature. This may have lead to higher lung volumes in swimmers. From the results of different strokers of swimmers, it is clear that lung volumes differ with respect to the stroke technique employed by the swimmer. Here the age and height, training duration of the swimmers performing different strokes were almost matched, so it is more or less clear that lung volumes are influenced by different swarming strokes. The results of the study can be utilised for the selection trials of swimmers. The study outlines the need for research work in swimmers to be more specific with regard to strokes than generalizing swimmers of different strokes as a category together.

Adult↗
PubMed1999

Spirometric impairments in undernourished children.

The present study elucidates the effect of undernutrition on pulmonary functions in children. The study was carried out in healthy normals, wasted, wasted and stunted children. Spirometry was performed with Vitalograph Compact-II spirometer. Wasted, wasted and stunted children showed lower lung volumes, forced mid expiratory flow time and inspiratory flow rates than healthy normals. Wasted and stunted children had lower VC, FVC and FIF50% than wasted children. The reduction in lung volumes and flow rates in wasted children may be due to ventilatory muscle wasting. But in wasted and stunted children along with muscular wasting diminished skeletal growth is also a reason for lower lung functions. No airflow limitation was observed in undernourished children.

Case-Control Studies↗
PubMed1997

Pulmonary function studies in rowers.

The present study attempts to investigate the pulmonary functions of snake boat rowers before and after rowing. This is made on 12 healthy traditional snake boat rowers ranging from age 16-23 years of Kavanattinkara boat race, Kottayam, Kerala, India. The pulmonary function tests were carried out with vitallograph compact-II spirometer. The results show a decrease in pulmonary functions "lung volumes" and "flow rates" after rowing in comparison to basal condition.

Adolescent↗
PubMed1997

Prediction equation for lung functions in South Indian children.

Lung functions including VC, IVC, FVC, FEV0.5, FEV1, PEF, FEF0.2-1.2, FEF25-75%, FEF75-85%, PIF, FMFT, MVV(IND), peak expiratory flow at 25%, 50% and 75% of FVC, peak inspiratory flow at 75%, 50%, 25% and the ratio between different lung volumes were measured with Vitallograph Compact-II spirometer on 109 South Indian school boys in the age group of five to sixteen years. The results show an increase in "lung volumes" and "flow rates" with increase in age, height and weight. FMFT and MVV(IND) also increase with increase in anthropometric measurements. All the lung functions except FEF75-85% and the ratio between different lung volumes show significant positive correlation with age, height and weight. Regression equations were derived for predicting normal lung functions for healthy South Indian boys. Lung volumes and flow rates were lower than North Indian and foreign boys. The decrease in lung functions in South Indian boys were due to their sea level dwelling, dietary habits and comparatively lower anthropometric measurements.

Adolescent↗
PubMed1997

Respiratory function during warm-up exercise in athletes.

The theme of the present study is to stress the importance of duration of warm-up exercise on respiratory functions in athletes. Significant improvements in athletic performance was achieved due to warm-up exercise owing to increase in blood flow, muscle and core temperature. The optimum intensity and duration are required to bring about the desired warm-up. A close examination on respiratory functions and its relationship with exercise has not been studied extensively. The present investigation is to explore the various respiratory functions in relation to the intensity and duration in preadolescent athletes before and after warm-up exercise. The results show a significant increase in vital capacity after 25 min and a significant reduction in FEV0.5, FEF75% and FEF25-75% after 45 min of warm-up exercise. The results suggest that a warm-up exercise of short duration (25 min) and mild intensity was beneficial than long duration (45 min) and intense exercise. Although the performance of athletes was not directly measured during exercise, these data demonstrate the benefit of warm-up.

Adolescent↗