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S Sohlberg

Publications and source records attributed to S Sohlberg.

At least 19 recordsLinked to original sources

Methodology in subliminal psychodynamic activation: the next step in the debate.

Subliminal psychdynamic activation methodology has recently been the subject of an exchange of views between Birgegård and Sohlberg (1999) and Fudin (2000). The agreements and some remaining points of contention are summarized here. The main difference of opinion appears to concern unconscious verbal encoding in relation to subjective experience in subliminal stimulation and whether subliminal psychodynamic activation results are unreliable until a full explanation of how verbal encoding works is at hand. We conclude that clarifying perspectives is important and that those suggesting alternative explanations of results on subliminal psychodynamic activation must now empirically investigate their claims.

Humans↗

New methodological advice for research in subliminal psychodynamic activation.

Recent integration among approaches to perception without awareness has brought the usefulness of Subliminal Psychodynamic Activation into renewed focus. Several authors have discussed the possible detrimental impact on interpretation when control phrases are used that for some participants may be less than affectively neutral (e.g., Fudin, 1986; Greenberg, 1997). In this continuing commentary, we argue that the neutrality of a substantive stimulus is an insoluble issue, and instead the suitability of controls for a given study should be emphasized. Also, we discuss the apparent confusion between experimental psychodynamics and efforts to answer Greenwald's 1992 "two-word challenge."

Awareness↗

Depression, gender and identification: replication and extension.

Replicating pilot findings, this study (N = 100) suggests that identification processes are a factor in the aetiology of depression. These processes are gender-linked: identification with father is more important for males, identification with mother for females.

Adult↗

Stroop and mood/memory measures in the study of unconscious "oneness".

Adaptive behavior following subliminal stimulation with "Mommy and I are One" (MIO) is a poorly understood finding. Positive mood may explain adaptive behavior, but we replicated an earlier finding that effects can also include negative mood. Color naming in a Stroop paradigm was slower on "symbiosis" words (Cohen's d = .19 to .56). Perhaps a "oneness" structure if primed has different affective correlates in different participants.

Affect↗

Evaluation of the dorsal aorta cannulation technique for pharmacokinetic studies in Atlantic salmon (Salmo salar) in sea water.

The antimicrobial drug flumequine was given intravascularly and orally to cannulated and non-cannulated Atlantic salmon (Salmo salar) in sea water at 11 degrees C. The cannulated fish were divided into two groups, which were given flumequine (25 mg/kg) intravenously into the caudal vein (n = 8) and orally via a stomach tube down the oesophagus (n = 8). After a washout period of 2 days, the intravenously administered fish were given the drug orally, and the orally administered fish were given the drug intravenously. Blood samples were taken at different time points after drug administration through a cannula inserted into the dorsal aorta. The fish in the non-cannulated group were either given flumequine intravenously or orally, and blood samples were collected by killing five fish at predetermined time points after administration. The haematocrit values were measured in all the fish daily for 4 days after drug administration and thereafter, in all the collected blood samples throughout the whole experiment. The haematocrit values differed significantly between the cannulated and the non-cannulated fish. We found low haematocrit values and slow drug elimination in the cannulated groups, compared with higher haematocrit values and faster drug elimination in the non-cannulated groups, but further investigations are needed to prove any causal relations of this observation. The volume of distribution (Vd(ss)) was twice as large in the cannulated groups compared with the non-cannulated group, in the fish administered the drug intravenously. In the last part of the elimination phase, the half-lives differed considerably between the cannulated and the non-cannulated groups both after oral and intravenous administration. The slower depletion of the drug concentration in the plasma of the cannulated fish is due to the large Vd(ss) as there are only small differences in clearance (ClT) between the groups. In this study the elimination of flumequine in cannulated Atlantic salmon differed from the elimination of flumequine in non-cannulated Atlantic salmon.

Administration, Oral↗

Co-occurrence of ego function change and symptomatic change in bulimia nervosa: a six-year interview-based study.

Low ego strength is theoretically thought of as causing difficulties in interpersonal relations and leading to the development of psychiatric symptomatology. Patients with bulimia nervosa were previously shown to have low ego strength and were studied to investigate whether gains in ego strength occur over time and are associated with improvement in symptoms. The average patient had an ego strength at a borderline level at index and at a neurotic level 6 years later. Less positive change in ego strength was associated with a low initial Eating Disorder Inventory (EDI) Symptom score a long Time in Treatment, and having been referred for specialist care. Positive changers significantly more often stopped vomiting/abusing laxatives and showed several non-significant tendencies to improve in other symptomatic aspects as well. Several methodological caveats are discussed, but these findings may contribute to the identification of mechanisms whereby long-term improvement occurs in bulimia nervosa.

Adult↗

Personality in Anorexia nervosa: an update and a theoretical integration.

No single cause is likely to be of supreme importance in the etiology of Anorexia nervosa, but personality factors continue to attract researchers' attention. This paper is a review of evidence on the subject, covering psychometric, interview, and projective investigations. Significant methodological problems exist in the literature, but do not suffice to explain findings of obsessive and inhibited features intermixed with impulsivity, and a high prevalence of defined personality disorders. Adding to previous work by Cloninger and Strober we suggest that vulnerable individuals are temperamentally incapable of coping with the challenges of adolescence by anything other than repetitive, reward seeking behavior. In a social environment that greatly emphasizes thinness as a criterion for self-worth and success, the outcome may be Anorexia nervosa.

Anorexia Nervosa↗

A comparison of some of the pharmacokinetic parameters of three commercial sulphadiazine/trimethoprim combined preparations given orally to pigs.

Three sulphadiazine/trimethoprim preparations were administered orally during feeding to pigs. Six male and six female pigs were used. Clinically important pharmacokinetic parameters of the two drugs in the three preparations were determined and compared. The plasma concentrations of sulphadiazine and trimethoprim increased rapidly in the pigs followed by a quite rapid decrease from 4 to 12 h after oral administration. The mean values of the absorption half-lives of sulphadiazine and trimethoprim were 0.9-1.6 h and 0.5-0.8 h, respectively. The corresponding values for the elimination half-lives of sulphadiazine and trimethoprim were 3.1-4.3 h and 3.4-6.0 h, respectively. There were no significant differences between the pharmacokinetic parameters of the two compounds in the three preparations with the exception of Tmax for sulphadiazine and t 1/2 beta for trimethoprim. Comparative bioavailability calculations showed no statistically significant differences between sulphadiazine and trimethoprim in the three preparations. The weight increase of the pigs during the experimental period (mean = 37.3-64.9 kg) did not cause differences in the kinetics of the two drugs which could have consequences for the use of the three combined preparations in clinical practice. No unacceptable or antibacterial residues of sulphadiazine or trimethoprim were found in the kidneys of pigs slaughtered at 5, 7 and 10 days after administration.

Administration, Oral↗

Personality, life stress and the course of eating disorders.

We tested whether personality disturbance and stressful life events can help explain why some patients with Anorexia nervosa or Bulimia nervosa remain ill for several years. In a follow-up of 37 patients, both factors were found to be significantly associated with a poorer outcome after a year, and preliminary data suggest this trend continues after two years. Further follow-up is necessary, but the data so far suggests that treatment goals and methods must be tailored to widely dissimilar needs. They also imply that therapeutic efforts to help patients cope with stressful events may be rewarded by measurably reduced morbidity.

Adolescent↗

Impulsivity and long-term prognosis of psychiatric patients with anorexia nervosa/bulimia nervosa.

Few if any reliable indicators of long-term outcome have been found in eating disorders. Impulsivity was the strongest predictor in the present study of 35 adults with anorexia nervosa or bulimia nervosa. This variable accounted for 25% of anorectic symptoms at 2 to 3 years follow-up and 14% at 4 to 6 years (Eating Attitudes Test). The relationship was specific insofar as impulsivity predicted neither depression nor overall mental health. Cognitive impairment may be one reason for the poor prognosis of impulsive patients.

Adult↗

Ego functioning predicts first-year status in adults with anorexia nervosa and bulimia nervosa.

Severe personality disturbance is a feature that possibly explains chronicity in eating disorders, a largely inexplicable development in terms of previously investigated factors. We tested this hypothesis in a group of 41 anorectics and bulimics with ratings of 13 ego functions and of status at 1-year follow-up. Patients who still were preoccupied with weight or shape and had a DSM-III-R eating disorder at follow-up had more severe ego disturbance at initial presentation than those who were free from symptoms. The relevance of demographics, syndromal diagnosis and clinical factors other than ego functioning was limited. The importance of ego functioning for prognosis in eating disorders thus appears to overshadow that of several factors that have been extensively cited in the literature.

Adult↗

Eating Disorder Inventory in Sweden: description, cross-cultural comparison, and clinical utility.

The Eating Disorder Inventory is one of very few tests for anorexia nervosa and bulimia nervosa that measures not only symptoms but also psychological characteristics believed to be central in these disorders. This study of 425 patients and control subjects showed that patients had markedly higher scores than controls and recovered patients on all eight scales. Individuals with bulimia nervosa scored higher on a few of the scales than those with anorexia nervosa, as did binge eaters at all weights compared with those who only restricted eating. Comparison with Canadian subjects showed several differences in normal controls. Since the technical properties of our Swedish version of the EDI were excellent, these differences may be meaningful rather than artifacts of the translation. Finally, the analyses indicated that the EDI may be useful for purposes of screening for eating disorders, and possibly for differential diagnosis.

Anorexia Nervosa↗

Eating disorders in patients with insulin-dependent diabetes mellitus.

The frequency of anorectic/bulimic disturbances in a sample of male and female subjects with insulin-dependent diabetes mellitus was compared to that of male and female normal controls. The results suggest an overrepresentation of anorexia/bulimia in the female diabetics. Prevalence of eating disorders was determined from the scores on the Eating Attitudes Test. As a group, the female diabetics had significantly (p less than .05) higher scores on the test, suggesting a greater "awareness" of topics related to food and eating. The results are discussed within a risk-factor model, in which insulin-dependent diabetes mellitus may be viewed as one factor in the development of eating disorders.

Adult↗