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Biomedical subjects

S Stosić

Publications and source records attributed to S Stosić.

At least 19 recordsLinked to original sources

[Vascularised osteocutaneous scapular flap in the reconstruction of mandibular defects after war wounding].

Vascularized osteocutaneous scapular flaps belong into the most convenient ones in reconstruction of mandibular defects followed by massive loss of adjacent skin and mucous membrane due to its vascular supply, bulkiness, suitability and mobility of cutaneous component of the flap. In seven wounded patients such defects of the mandible and adjacent soft tissues after war wounding have been reconstructed at the Clinic for Maxillofacial Surgery of the Military Medical Academy - Belgrade during the six years period with vascularized osteocutaneous scapular grafts. Here we present localization and structure of the defect, features of harvested compound graft, the procedure of reestablishment of mandibular continuity, immediate and late complications during the consolidation period, as well as the analysis of the success rate.

Humans↗

[Reconstruction of the long bones and mandible with vascularized fibular grafts].

In two prospective studies at the Clinic for Plastic Surgery and Burns and Clinic for Maxillofacial Surgery of the Military Medical Academy in the period from 1991 to 1996 we performed 47 transplantations of the vascularized fibular graft in order to compensate bone defects of the long bones and mandibular inflicted by war wounding. The importance of the length of the vascular pedicle preparation for the total success was pointed out as well as the immobilization of the elbow region for the compensation of the defects of the upper arm and forearm and total healing of the mandibular for the later functional rehabilitation. The realized primary efficiency of 70.2% and total successfulness of 93.6% indicated that at the compensation on of bone defects the etiology of war wound could be compared to the etiology of malignant tumors resection and trauma.

Adolescent↗

[Ultrasound as a diagnostic aid in maxillofacial surgery].

Ultrasonography is a relatively new diagnostic aid in maxillofacial surgery. It can be used in maxillofacial surgery in three modifications: Doppler sonography, A-scan sonography, B-scan sonography. As clinicians we wanted to determine what contribution ultrasound examination has made to the diagnosis of superficial maxillofacial masses, when compared with clinical examination, intraoperative findings and with other methods of investigations. Since 1985 B-scan sonography has been performed in the examination of congenital, inflammatory and neoplastic masses of the head and neck on more than 1500 patients. The ultrasound examination was performed in the Department of Radiology by radiologists. The value of the ultrasound findings varied depending on the soft tissue lesions which were examined and the experience of the radiologists who performed the examination. The advantages of the diagnostic ultrasound are in being noninvasive, without any known deleterious biological effect, rapid, painless, inexpensive and easily reproducible. Ultrasonography is a procedure which nowadays is routinely performed in our department for the preoperative evaluation of our cancer patients and postoperative follow-up as well as for the patients with inflammations, diseases of the salivary glands and soft tissue swellings.

Head and Neck Neoplasms↗

[Use of Bernard's diadynamic current in evaluating recovery of pain sensitivity in transplanted microvascular flaps].

The application of microvascular transfer of tissues provides a single act transplantation of free flaps to any part of the body. Following the operation, free flaps are nerveless. By spreading out of nerves from the recipient region surrounding into the flap tissue, transplanted free flaps become reinervated. The sensitivity of the transferred free flaps is very important in feet, palms, breasts, genitals, face etc. The aim of our research was to use Bernard's diadynamic currents in establishing the time needed for recovery of the transferred flap's pain sensitivity in comparison with the recipient region's surrounding. At the Clinic for Plastic Surgery and Burns and Clinic for Physical Medicine and Rehabilitation of the Military Medical Academy, we used Bernard's-diadynamic current to analyze the recovery of the pain sensitivity in 33 patients with transferred free flaps. The first tests were performed six moths after the free flap transfer and were repeated in the intervals of 6 to 36 months. The pain recovery was tested in 5 cutaneous, 18 myocutaneous and 10 osteocutaneous flaps transplanted to foot-10, lower leg-13 and head-10. Pain sensitivity in the transferred flaps was detected 6 months after the free flaps transfer and was definitely ascertained 12 months after the operation. Current of 10.11 mA was required to reach the pain sensitivity threshold after the first six months and 8.52 mA after 36 months. It is obvious that the pain sensitivity threshold is significantly higher in the transferred free flaps (p < 0.001) than in the donor or recipient regions' surroundings.

Electrodiagnosis↗

[Sebaceous gland function in transplanted microvascular flaps].

Sebaceous glands produce sebum that contains: triglycerides, esters of cholesterol, and sometimes even pure cholesterol, squalene and esters of wax. Microvascular transplantation exposed the tissue of free flaps to the temporary ischemia and anaerobic metabolism, inflammatory, denervative and reinnervative processes. The sebaceous glands of the free flaps were also exposed to the action of physiopathologic processes during the micro vascular transfer. Because of that, the function of the sebaceous glands of the transplanted free flaps was estimated compared to the function of the sebaceous glands of the recipients and donor's region environment. The investigation of the sebaceous glands of free flaps function has been performed in 32 wounded patients at the Clinic for Plastic Surgery and Burns, and Institute for Medical Biochemistry of the Military Medical Academy. All the wounded have undergone the microvascular transplantation of the cutaneous, myocutaneous and osteocutaneous flaps. Dry residue in either of the soluble substances was measured in the period from six to thirty six months after the transplantation. The obtained results indicated that the function of the sebaceous glands of the transferred flaps 25.36 months after the transplantation was weaker than the function of the sebaceous glands of the recipients and donor's region's environment and amounted to 98% of the function of the sebaceous glands of the recipient is region's environment.

Adult↗

[Blood autotransfusion in head and neck surgery].

Autotransfusion as a method of blood compensation after multilative surgical operation in cases of malignant neoplasm of the maxillofacial region, was introduced in our clinical practice in 1989, and up to now we have performed it in a group of 23 patients. It has been known that an autotransfusion depends on the patients' general health situation, hemoglobin level, hematocrit and iron concentration in serum. We exfused at least three days before operation 450 ml of blood from each patient. The blood was taken into plastic bags and kept in the refrigerator at the temperature of +4 degrees C. The decrease of serum iron concentration was approximately 54.26% in all tested patients that demanded the substitution therapy with iron together with vitamin C before and after surgery. There was neither prolongation of postoperative treatment nor complications associated with this method of post-operative blood loss compensation. Based on obtained results we could conclude that the best method of inter- and postoperative blood compensation was autotransfusion, taking care about factors which could limit the possibilities of its applications.

Adolescent↗

Maxillofacial war injuries during the war in former Yugoslavia.

War wounds of the maxillofacial region occur in 5-17% of casualties. In the Clinic for Maxillofacial Surgery of the Military Medical Academy, during the war in former Yugoslavia, 482 casualties with dominant wounds in the maxillofacial region were treated. The outcome of the treatment depended on the quality and speed of the first aid and general medical aid, as well as on qualified specialist treatment. Specificity of the management of the war wounds of maxillofacial region includes: minimal debridement of soft tissues, removal of only deperiosted fragments of bony tissues, valid reconstruction of bony and soft tissues defects, correct immobilization, antitetanus prophylaxis, adequate antibiotic therapy, as well as permanent and very meticulous postoperative care.

Humans↗

The treatment of traumatic facial bones and jaw fractures in the period 1972-1996.

During the last twenty-five years, in the period from January 1, 1972 to December 31, 1996, 1006 injured with facial and jaw fractures have been treated at the Clinic for Maxillofacial Surgery of the Military Medical Academy--91.05% of the injured were males and 67.98% belonged to the age group between 11 and 30. The most frequent etiologic factors were traffic accidents (46.42%) and fights (38.07%). Isolated fractures of mandible were found in 51.09% of the injured. In 70.57% of the treated the surgery was used for adequate reduction, osteosynthesis and stabilization of bone fragments, and 29.34% of the injured were treated conservatively, which involved the manual reduction and intermaxillar immobilization. The post-operative complications were observed in 51 (5%) of the injured.

Adolescent↗

Monocortical osteotransplant of the iliac bone in reconstruction of mandibular gunshot defects.

In the Clinic for Maxillofacial Surgery of Military Medical Academy, 134 injured with mandibular defects were treated, as well as a significantly larger number of injured from the territory of former Yugoslavia, with dominant injuries of the head and neck regions. Until June 1994, smaller defects were treated using bicortical osteotransplant of the iliac bone. Due to its only partial successfulness in reconstruction of mandibular defects, monocortical osteotransplant of the iliac bone was selected for reconstruction of the mandibular defects and the results were much better compared to the other free osteotransplants.

Adolescent↗

Facial nerve injuries and its treatment.

Twenty four patients with traumatic interruption of the conductivity of the facial nerve were treated in the period 1991-1996 at the Clinic for Maxillofacial Surgery. After topographic orientation about the site and level of the injury, the reconstruction of the nerve using nerve grafts was performed in all patients. The results were satisfactory.

Facial Nerve↗

Vascularized fibular graft in the reconstruction of posttraumatic mandibular defects.

The results of the use of the vascularized fibular graft for the reconstruction of posttraumatic defects of the mandible are presented. Different surgical procedures were applied in reconstruction of the mandibular defects in 120 wounded. In the last four years vascularized fibular graft was used in 11 mandibular reconstructions. Taking into account the survival rate of 100%, long vascular pedicle, strength, length and the possibilities of adaptation of the bone make this graft suitable for mandibular reconstruction. The functional and esthetic results obtained by the use of this graft were satisfactory, with minimal donor site morbidity.

Adult↗