PubMed Health⌕ Search

Biomedical subjects

S Sundaresh

Publications and source records attributed to S Sundaresh.

2 recordsLinked to original sources

Supporting multi-level multi-perspective dynamic decision making in medicine.

Most medical decision problems are exceedingly complex and contain a large number of variables. Abstraction facilitates the process of building a decision model by allowing a model builder to work at a level of detail that he is most comfortable with; it is also useful in time-critical situations or when there is insufficient data to support complete specification of probabilities of the uncertain events. In this paper, we identify and formalize abstraction and refinement operations commonly used in model construction. We illustrate the use of these mechanisms with an example on the follow-up management of colorectal cancer patients after surgery.

Colorectal Neoplasms↗

Decision analytic approach to severe head injury management.

Severe head injury management in the intensive care unit is extremely challenging due to the complex domain, the uncertain intervention efficacies, and the time-critical setting. We adopt a decision analytic approach to automate the management process. We document our experience in building a simplified influence diagram that involves about 3000 numerical parameters. We identify the inherent problems in structuring a model with unclear domain relationships, numerous interacting variables, and real-time multiple inputs. We analyze the effectiveness and limitations of the decision analytic approach and present a set of desiderata for effective knowledge acquisition in this setting. We also propose a semi-qualitative approach to parameter elicitation.

Craniocerebral Trauma↗