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Biomedical subjects

S Szram

Publications and source records attributed to S Szram.

At least 19 recordsLinked to original sources
PubMed1992

Morphometric evaluation of myofibrillar mitochondria in experimental administration of ethylene glycol.

The authors carried out morphometric analysis of the surface, area, circumference and shape of myofibrillar mitochondria in rats submitted for acute experimental intoxication with ethylene glycol. The measurements were taken at 12 and 24 hours after intoxication and compared with those in the control group. A significant increase in mitochondrial circumference and surface area was seen as early as 12 hours with their shape being more rounded than elongated. At 24 hours of the experiment the parameters further increased. The use of computer image analysis permitted an objective and measurable confirmation of changes in electronograms and revealed the presence of disorders in the phase in which traditional methods were useless.

Acute Disease↗
PubMed1992

Ultrastructural signs of myocardial damage due to acute experimental intoxication with ethylene glycol.

The authors carried out ultrastructural studies of the myocardial sections from inbred Wistar rats in the course of acute experimental poisoning with ethylene glycol. It was shown that slight mitochondrial swelling with clearing of the matrix, myofibrillar edema with decreased electron density of the sarcoplasma and widening of channels of the smooth intraplasmatic reticulum were visible as early as at 12 hours after intoxication with no changes in light microscopy. The changes were located mainly in the subendocardial layer of the ventricles and papillary muscles. At later stages of the experimental ultrastructural changes markedly progressed. Mitochondrial swelling enhanced with destruction of mitochondrial crests, myelin-like figures formed, myofibrillar necrosis and contraction bands developed and segmental or complete dissection of the intercalated disk edges appeared. The chages were scattered all over the myocardium predominating in the subendocardial layer and papillary muscles.

Acute Disease↗
PubMed1992

[On primarily bifocal laryngeal carcinoma and bronchogenic cyst of the neck].

The authors discuss a problem of rarely occurring bifocal carcinomas with the presentation of their own case of laryngeal carcinoma and branchiogenic cyst of the neck. They pay attention to histopathologic features underlying the diagnosis of branchiogenic cyst carcinoma and to the necessity of oncologic alertness in tumors of these kinds.

Biopsy↗
PubMed1986

Xanthogranulomatous prostatitis.

Two cases of rarely observed granulomatous prostatitis are presented. Unspecific clinical symptoms and a close similarity in clinical course to prostatic adenoma or adenocarcinoma may be misleading and produce severe diagnostic difficulties even for an experienced urologist. Close cooperation with a pathomorphologist is necessary for their avoidance. Relying on published evidence the authors briefly analyse this nosological entity, the aetiology of which is still controversial.

Humans↗
PubMed1983

[Observations on the peripheral vascular network of the myocardium during infarction].

The patterns of microvascular network have been examined in myocardium of 61 patients which died of subendocardial or transmural myocardial infarctions. The microangiographic patterns of interventricular septum and ventricular wall with or without morphological lesions have been compared. The investigations are related to the differences in microvascularization of various morphological types of myocardial infarctions. Our study confirms the classification of myocardial infarcts into microfocal and massive types. It explains the milder clinical course of microfocal subendocardial infarctions.

Angiography↗