EFFECT OF GASTRIN I AND II ON THE SECRETION OF INTRINSIC FACTOR.
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Biomedical subjects
Publications and source records attributed to S T CALLENDER.
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Twelve subjects have been studied in whom oesophago-jejunostomy had been performed leaving the stomach in situ. All had considerable metabolic disturbance with steatorrhoea and inability to absorb vitamin B(12), and the operation has been abandoned in favour of oesophagojejuno-gastrostomy.
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The Kay augmented histamine test has been used in a special study of 30 patients with pernicious anaemia and 136 other subjects suspected of having achlorhydria. The findings have been correlated with uropepsinogen excretion, serum levels of vitamin B(12), and gastric biopsy. The definition of achlorhydria is specially considered.
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