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Biomedical subjects

S T Chernokul'skiĭ

Publications and source records attributed to S T Chernokul'skiĭ.

10 recordsLinked to original sources

[The morphofunctional changes in the perivascular and lymphoepithelial nodes of the respiratory organs following antigenic stimulation].

Morphological, experimental-immunological methods with mathematical analysis were used in 108 Wistar line rats in the pre- and postnatal ontogenesis to study the lymphoid structures of the trachea, bronchi and stroma of the lungs. Two types of lymphoid nodules were detected in the respiratory organs of rats and man: 1. perivascularly located in the wall of the trachea, bronchi and stroma of the lungs; 2. lymphoid nodules of the mucous membrane of the respiratory ways which have a different structure. The former are related to a common immune system of the internal milieu, the latter--to a common immune system of the mucous membranes. Antigenic stimulation revealed that formation of lymphoid structures is enhanced and more rapidly terminated as to functional maturation. Lymphoid structures play a decisive role in local immunity.

Animals↗

[Perivascular lymphoid nodules].

As a result of investigation of lymphoid formations in the walls of the human tracheobronchial tree and the pulmonary stroma by means of morphological and morphometrical techniques, certain regularity in arrangement of the perivascular lymphoid noduli has been stated along the course of the lympho- and hemomicrocirculatory bed links. The periarterial lymphoid noduli of the tracheobronchial tree have certain morphological similarity and some differences, when comparing them with usual lymphoid noduli.

Adolescent↗

[The age-related characteristics of the lymphoid structures in the human respiratory organs].

It was found that the wall of the tracheo-bronchial tree and the lung stroma of man has two types of nodules: those located in the mucous membrane and adjoining the epithelium and those located in the fibrous-cartilagenous part of the wall of the trachea, bronchi and stroma of the lungs. The latter serve the purpose of defense of the internal medium of the body. It was established that lymphoid nodules of the respiratory organs undergo age-related involution. According to the authors' classification perivascular lymphoid nodules and lymphoid nodules of the mucous membrane of the tracheo-bronchial tree belong to a single immune system of the internal medium and mucous membranes participating in immune homeostasis.

Aging↗

[Lymphoid tissue during phylo- and ontogenesis].

In the process of evolution lymphoid tissue is isolated from the single hemolymphatic system as central and peripheral organs of the immune system. However there remains a close relationship between the lymphoid and myeloid tissues in the forms of perivascular lymphoid accumulations in organs both in the phylo- and ontogenesis. In mammals and man the diffusely disseminated within the body perivascular lymphoid tissue if differentiated in organoid-perivascular lymphoid follicles which are regularly located along the course of links of the hemo- and lymphocirculatory bed.

Animals↗