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Biomedical subjects

S T Jensen

Publications and source records attributed to S T Jensen.

7 recordsLinked to original sources
PubMed1997

[Significance of playroom area for morbidity in day care centers in Copenhagen].

Absence due to illness among children in 24 daycare centres in Copenhagen was registered during two periods of one year each with a five year interval. The results from the first period have been reported earlier. In each period, the physical, environmental, hygienic and social conditions of the institutions were assessed, and the playroom area per child was registered. The total number of children increased from 855 in the first period to 921 in the second because 13 of the 24 institutions had increased their capacity in the intervening period. On average, the playroom area per child decreased with 0.27 square metre per child in the 13 institutions with an increased number of children. All children were less than three years of age. Absence due to sickness constituted 7.6% of the days during which the institutions were open. For the second period, where the childrens age had been exactly registered, the effect of age on absence due to sickness was found to be statistically significant. The direction of the effect was a decrease in illness with increasing age. However, due to a high correlation between age and time attending the institution, the effect of age could not be separated from the similar effect of length of time that the child had attended the institution. It was found that sickness will decrease with 7.8% per month that the age of the child and time attending the institution is increased. A statistically significant connection was found between the playroom area per child and absence due to sickness after correction for the influence of age in a multivariate analysis. In conclusion, the sickness will decrease with 10.8% per square metre the playroom area per child is increased.

Air Pollution, Indoor↗
PubMed1992

[Morbidity of children attending day care centers in Copenhagen illustrated by social, physical, environmental and hygienic factors].

Sick leave among the children in 24 day nurseries in Copenhagen was registered during a period of one year. The physical, environmental and hygienic conditions of the institutions were assessed by means of interviews and inspection, supplemented by information from the local authorities. Sick leave constitutes 7.5% of the days during which the institutions were open and the average number of sick days per child varied from 14.6 to 24.4. Comparisons with similar investigations are inclusive on account of variations in the methods of registration and age distributions. It was characteristic of the institutions investigated that these included a number of old institutions in flats, many in streets with considerable traffic and where the conditions of ventilation and space do not conform with present-day standards. In some of the institutions, the hygiene is unsatisfactory, particularly where ventilation, outdoor activities and hand-washing are concerned. A statistically significant connection was found between amount of traffic at the institution, the hygiene and playroom area per child, on one hand, and absence due to sickness, on the other, as assessed by a statistical model for sick leave for child in a given institution. In order to prevent sickness, it is concluded that efforts to improve hygiene and space are desirable and, similarly, further research concerning the effects of atmospheric pollution is relevant.

Air Pollution, Indoor↗
PubMed1980

Intramuscular sedation technique.

A sedative technique with meperidine hydrochloride and promethazine hydrochloride via an intramuscular injection is presented. We believe this is an excellent technique because of the safety to the patient and the ease of administration. Like any technique using potentially dangerous medications, practitioners and their staff must be familiar with and prepared for possible complications. When the technique is mastered, it will be a valuable addition for treatment of certain mentally and physically handicapped patients.

Anesthesia, Dental↗
PubMed1975

A morphometric study of normal human liver cell nuclei.

Using the projecting method, measurements were made of the size of nuclei of liver cells in liver biopsies taken from ten patients with normal liver histology and normal liver function tests and from two patients with acromegaly. For the statistical analysis a parametric model of the distributions of the nuclear radii, the chi distributions, was used, making an estimation of the frequencies of di-, tetra- and octaploid nuclei possible. The distribution of the lengths of the nuclear radii was consistent with normal distributions corresponding to the different ploidy classes. Diploid nuclei constituted 84 to 99 per cent of the liver cell nuclei, and the frequency of polyploid nuclei increased with increasing age. Samples of nuclei within the same biopsy revealed significant differences in the mean radius of diploid nuclei and in the frequency of polyploid nuclei. This biological variation must be taken into account in the interpretation of karyometric data. One of the patients with acromegaly had a higher frequency of polyploid nuclei than seen in normal patients, and in both patients with acromegaly the size of diploid nuclei was large compared with normals. The frequency of binuclear nuclei was unrelated to age and frequency of polyploid nuclei, but males were found to have more binuclear liver cells than females.

Acromegaly↗
PubMed1975

Karyometry of liver biopsies in virus hepatitis.

Liver biopsies from ten patients with clinically mild or moderate acute virus hepatitis, taken in the acute phase of the disease and in the recovery phase or later, were assessed for the size of liver cell nuclei and the number of binuclear nuclei. A parametric model of the distributions of the nuclear radii was used to estimate the mean nuclear radius of diploid nuclei and the frequencies of di-, tetra- and octaploid nuclei. During the acute phase of virus hepatitis the liver cell nuclei were often larger, with greater variation in size, than in the recovery phase. This pleomorphism was not only due to pyknotic and necrotic nuclei as these were not measured. It is assumed that the enlargment of the nuclei was due to increased metabolic activity of the nuclei. The frequencies of polyploid nuclei and binuclear liver cells were higher in the first biopsies, probably reflecting regenerative activity. No correlation was found between the severity of the disease as judged by liver histology or routine liver tests and the degree of nuclear changes with respect to size and frequency of polyploid or binuclear liver cells.

Acute Disease↗