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Biomedical subjects

S T Momii

Publications and source records attributed to S T Momii.

4 recordsLinked to original sources

A data acquisition system for clinical research.

We developed a system for automatic collection and synchronization of multiple physiological variables during clinical investigations. Centered around an eight-track instrumentation tape recorder, the system solves several problems encountered in gathering this type of research data: (1) slowly changing variables are digitized and compressed onto a single track by recording them in one serial message, allowing for recording many more variables than there are tape tracks available; (2) simultaneous analog recording allows retention of original data for variables that may be processed subsequently by multiple schemes; (3) data acquisition is verified with both analog chart recording and numerical video display monitors; (4) off-line computer processing time is decreased at least twofold by using tape playback speeds faster than the recording speed; (5) cost is kept low by using an inexpensive 1/4-inch (0.64-cm) tape medium and dedicated microcomputers; and (6) the system is unobtrusive, portable, and easily reconfigured for different clinical studies. It proved to be reliable in a study of more than 80 patients undergoing cardiac surgery.

Computers↗

A gas-stream heater to control local skin temperature under evaporative sweat capsules.

A compact 4-W gas-stream heater for use with ventilated sweating capsules is described. The heating element is constructed from two modified 75-omega power resistors connected in parallel and contained in the capsule gas inlet tube. Heater power is controlled with integrated circuits which compare the output of a thermocouple, measuring either capsule skin or air temperature, with a predetermined target temperature. The unit responds fairly slowly to sudden large changes in target temperature, but once a steady state is achieved, maintains target temperature levels despite changes in evaporative heat loss. The device is well suited for studies in which local skin temperature or capsule air temperature must be elevated and clamped while the effects of other local stimuli or central thermoregulatory activity are studied, and in studies where the skin temperature effect on transepidermal water loss must be controlled.

Humans↗

Hydration characteristics and electrical resistivity of stratum corneum using a noninvasive four-point microelectrode method.

We have used a four-microelectrode probe to study the relationship between electrical resistivity (p), water content (wf) water binding, and electrolyte levels in samples of plantar stratum corneum. Untreated samples characteristically showed an exponential relationship between log p and wf. This characteristic was retained but altered quantitatively by factors which increase and decrease the ratio of bound to unbound water, by lipid extraction, and (following extraction) by electrolyte presoak. The theoretical aspects of obtaining similar data from intact stratum corneum are discussed.

Body Water↗