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Biomedical subjects

S T Zwas

Publications and source records attributed to S T Zwas.

At least 55 records · Page 3Linked to original sources

Scintigraphic assessment of ectopic splenic tissue localization and function following splenectomy for trauma.

Twenty-three subjects who had a splenectomy as a result of trauma underwent scintigraphic evaluation with a sensitive heat-denatured 99mTc-labeled red blood cells (DRBC). This method enabled detection of ectopic splenic tissue foci (ESTF) as small as 1 X 1 cm in diameter. ESTF splenosis or accessory spleen was detected in 15 cases (65%), a higher incidence than previously reported. The size of the ESTF ranged from 1 X 1 to 5 X 10 cm (0.8-40 cm2), and 53% were less than 2 X 2 cma (3 cm2). A new multiparametric scintigraphic evaluating technique is described, which estimates the quantity of ESTF and its grade of activity, relative to that of the liver. The technique is a highly efficient assessor of ESTF function. Good correlation was found between the size and activity of the ESTF and the presence of Howell-Jolly bodies (HJB), but with a low sensitivity for detecting small ESTF. Correlation was low between residual splenic tissue and concentrations of IgM, IgA and IgG immunoglobulins. The 99mTc-DRBC method described is recommended for verification of ESTF existence, localization, and function.

Adult↗

Indirect cervical lymphoscintigraphy in healthy subjects via submucosal cheek injections.

A new method of cervical lymphoscintigraphy is presented. It was performed on 16 healthy individuals via bilateral submucosal cheek injections with 99mTc-rhenium-sulfide-colloid. The ipsilateral uptake by the lymphatics on each side of the neck was consistently demonstrated in 15 subjects and allowed a comparative evaluation of the cervical lymphatic chains, including the submental, submandibular, jugulo-digastric and jugulo-omohyoid. The transverse cervical chain was demonstrated in 10 of 16 subjects. The method is simple, reliable and capable of clearly visualizing the lymphatic drainage of the oral cavity.

Adult↗

Unusual scintigraphic presentation of a shifting Meckel's diverticulum.

A Tc-99m red blood cell (RBC) study in a child with acute gastrointestinal bleeding of unknown origin suggested Meckel's diverticulum because of free pertechnetate uptake in the ectopic gastric mucosa. This finding has not been reported in the literature. A scan with Tc-99m pertechnetate then demonstrated a focal area of uptake with an unusual pattern of abdominal shifting consistent with a Meckel's diverticulum. A large Meckel's diverticulum containing gastric mucosa was found at surgery. A shifting pattern of focal uptake on a meckelogram study should be included among the diagnostic criteria for Meckel's diverticulum.

Child, Preschool↗

Scintigraphic demonstration of acute gastrointestinal bleeding caused by gallbladder carcinoma eroding the colon.

Massive lower gastrointestinal (GI) bleeding caused by gallbladder carcinoma eroding into the colonic wall was demonstrated accurately by Tc-99m RBCs. In addition, retrograde bleeding into the gallbladder was also identified while arteriography did not show contrast extravasation. This case supports the use of Tc-99m RBCs over Tc-99m sulfur colloid for more accurate localization of lower GI bleeding.

Acute Disease↗

Apathetic thyrotoxicosis due to hemorrhage into a hyperfunctioning thyroid nodule after excessive anticoagulation.

Hyperfunctioning thyroid nodule was diagnosed in a 72-year-old woman. When the nodule reached a diameter of 3.5 cm, overt thyrotoxicosis of the apathetic type was precipitated by hemorrhage into the nodule during a period of excessive anticoagulation. All abnormal physical signs and symptoms as well as laboratory findings returned to normal within a month, without any specific treatment. It was possible to follow this process by repeated B-mode sonographic examinations and thyroid scans.

Adenoma↗

Use of radionuclide method in preoperative and intraoperative diagnosis of osteoid osteoma of the spine. Case report.

A 24-year-old man with persistent low back pain and right sciatica, was found to have an osteoid osteoma of the right pedicle of the second lumbar vertebra. 99mTc-MDP bone scan and CAT scan produced an early diagnosis of the lesion. Intraoperative 99mTc-MDP in vitro combined with imaging and quantitative activity measurements were useful for accurate localization and complete removal. The method is simple and can be performed in every nuclear medicine department, with no need for special operating room facilities.

Adult↗

Diagnosis of jugular paraganglioma by radionuclide angiography: concise communication.

Jugular paraganglioma is a highly vascular tumor, slowly growing, extending into the surrounding structures and causing otologic and/or neurologic symptoms according to its location in the jugular bulb region or the middle-ear. In our study, modified vertex and posterior head scintiangiography was used in seven cases. Scintiangiography was positive in all seven, whereas concomitant radiographic studies were limited: four of the seven gave positive findings by transmission computerized tomography (TCT). Only four patients underwent angiography, with positive results in two. Hypocycloidal tomography was positive in three cases. However, some radiographic studies, particularly TCT, may be useful in detecting local extension, bone destruction, and soft-tissue infiltration. Radionuclide angiography proved highly reliable and should be used initially whenever a jugular paraganglioma is suspected.

Aged↗

Significance of ultrasound and gallium scanning in detecting intraabdominal abscesses.

The diagnostic value of ultrasound was compared to that of gallium scan in 36 patients with clinically suspected intraabdominal abscessed. Both modalities reached an accuracy of 91.6%. The gallium scan was found to be more sensitive (93.3%) than ultrasound (86.6%), while the specificity rate of ultrasound (95.2%) was superior to that of the gallium scan (90.4%). It is suggested that, in the acutely ill patient, ultrasound should be the method of choice, whereas in the nonacute patient, either method may be used. A positive ultrasound examination and a negative gallium scan can be considered conclusive, whereas a negative ultrasound study or a positive gallium scan needs the complimentary support of the other modality in order to reach a definite conclusion.

Abdomen↗

Brain scintigraphy in arteriovenous malformation.

Brain scintigraphy demonstrated an unusual image pattern which was associated with an arteriovenous malformation (AVM). A preoperative diagnosis of AVM was suspected on the radionuclide study and confirmed by contrast angiography and surgery. We review the criteria established for diagnosis of AVM by dynamic and static scintigraphy and discuss additional findings which can be helpful when noncharacteristic AVM presentations are encountered.

Adult↗

Thoracoscintigraphy in the differential diagnosis of cardiomegaly.

"Thoracoscintigraphy" is a radioisotopic scanning technique for demonstrating the nature of an enlarged cardiac shadow found on chest X-ray. The technique consists of superimposing scintiscans of the cardiac blood pool, the liver and the lungs and comparing the outline of the cardiac blood pool image with the cardiac shadow seen on X-ray. With this procedure the correct diagnosis of pericardial effusion was made in 11 of 15 patients and of pure cardiac dilatation and/or myocardial hypertrophy in three patients. In one of the patients the thoracoscintigraphic diagnosis was equivocal. Thoracoscintigraphy clearly demarcates the cardiac shadow from the surrounding organs, delineates the intracardiac blood pool within the cardiac shadow and indicates the best approach for pericardiocentesis. The procedure is harmless and noninvasive, and the radiation exposure is low and safe.

Adult↗

Head and brain scan findings in rhinocerebral mucormycosis: case report.

Brain and bone scan findings in two patients suffering from rhinocerebral mucormycosis following kidney transplantation are presented. Two patients who had had kidney transplants and were sustained for over a month on immunosuppressive drugs developed a rare type of opportunistic infection--mucormycosis. They were examined in various stages of their disease. Special attention was paid to the scintillagraphic findings.

Adult↗