[Vesico-ureteral reflux in children].
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Biomedical subjects
Publications and source records attributed to S Taksdal.
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In a case of incomplete duplication of the male urethra the interurethral septum was divided by scissors. After this simple operative procedure, the patient was relieved of his obstructive symptoms. Postoperative urethrography revealed considerable improvement of the calibre of the urethral lumen, and uroflowmetry showed almost normalized flow values. This technique is recommended as treatment in similar cases.
The role of the lymphatics in the regurgitation of bilirubin during acute and chronic extrahepatic cholestasis in the dog was studied after intravenous injection of 14C-bilirubin. In acute cholestasis the injected labelled bilirubin was rapidly removed from plasma and reappeared in thoracic duct lymph as labelled bilirubin conjugates. No labelled conjugates were at any time demonstrated in plasma. This is most easily explained as a result of a bilio-lymphatic regurgitation. In chronic cholestasis the labelled bilirubin conjugates were delivered back into the blood, and no specific transport function of the lymph was found. Our results indicate a change in liver cell secretory direction in long-standing cholestasis.
A case with traumatic renal arteriovenous fistula is presented. The diagnosis was established by selective renal angiography. The fistula was treated by ligation and division of the feeding artery. Postoperative angiography revealed complete closure of the fistula. The aetiology, clinical manifestations, diagnosis and treatment of renal arteriovenous fistula are discussed.
The role of the liver lymphatics in the regurgitation of bilirubin during the different stages of cholestasis has been a matter of debate. Earlier studies have shown that 14C-bilirubin injected intravenously one hour after induction of cholestasis was rapidly and completely cleared from the blood and appeared in the thoracic duct lymph in high concentration. During chronic cholestasis the injected 14C-bilirubin was delivered directly back to the blood after conjugation in the liver. The aim of the present study was to investigate the role of the lymphatics in the transport of non-erythroid bilirubin (NEB), a metabolic product of certain tissue haemes, produced mainly in the liver. The study was carried out in dogs. Five dogs were studied in the first hours following bile duct obstruction, and five others after at least one week of cholestasis. 14C-delta-aminolevulinic acid was given as a NEB precursor. In contrast to the results obtained with 14C-bilirubin injection, evidence for a delivery of conjugated labelled NEB directly to the blood during acute cholestasis was found. The concentration curves for NEB and non-NEB radioactivity in the thoracic duct lymph indicated the presence of a secondary biliolymphatic regurgitation. In chronic cholestasis no evidence for such a biliolymphatic regurgitation of NEB was found.
Doxycycline was administered orally to 23 patients scheduled for prostatectomy or radical cystectomy. Blood and prostatic tissue samples were collected simultaneously during operation and subsequently assayed for doxycycline levels. The concentration of doxycycline in the prostatic tissue was on average 2.75 mug/g which is far above the therapeutic level. The lowest level recorded was 0.85 mug and the highest was 4.81 mug. The findings suggest a tendency for this antibiotic to accumulate in prostatic tissue. This is in agreement with the clinical observations of the good effect of doxycycline treatment in patients with chronic bacterial prostatitis.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.