Biomedical subjects

S Trepte

Publications and source records attributed to S Trepte.

3 recordsLinked to original sources

PubMed2005

Internet-based quality assurance registry for LDL apheresis QUASA--the apheresis registry.

Quality assurance measures have been demanded in the execution of extracorporeal LDL apheresis therapy (LDL apheresis) by the NUB-guidelines of the national committee of physicians and health insurance. The measures apply to specialist, organizational and mechanical requirements for the execution and billing of this method of treatment. Furthermore, as a result of the legal requirements of the SGB V, complementary BUB-guidelines were introduced in 1999. These should prove the therapeutic benefit of an LDL apheresis treatment. Beyond assuring quality of performance, documentation of the treatment is explicitly demanded. For the past two years, the non-profit QUASA gGmbH has developed a quality assurance registry for LDL apheresis based on those requirements. Since March 2003, the apheresis physicians can voluntarily take part in this registry through the internet. Beside the patient's medical history, data relevant to the treatment are also recorded. Because of the analysis of the national clinical data it will be possible for the first time, for the medical profession to fulfill the guidelines and ensure the quality of LDL apheresis.

Blood Component Removal↗

PubMed2004

[Ozone decline and UV increase].

The following results have been obtained from long-term observations on the ozone layer and UV at the Meteorological Observatory Hohenpeigenberg:The seasonally varying decline of the ozone layer determines the maximum exposure to UV. Since ozone decline shows the highest rates in the spring months the UV exposure has most strongly increased in this time of the year. This is especially important because in spring the human skin is not adapted to UV exposure. Weather changes from day to day can induce rapid ozone reductions in spring about -30% which in turn is followed by an increase in UV of about 40%. Clouds, especially the transparent cirrus clouds (high clouds consisting of ice particles) have increased in frequency during spring and fall while a decrease is observed in summer. This change in cloudiness reduces the daily UV dose in spring and fall while it is enhanced in summer. With increasing height above sea level UV rises by roughly 10% per 1000 m (rule of thumb). Snow reflects the UV-radiation by up to 80% enhancing the UV-doses at relevant conditions. Strong volcano eruptions destroy ozone in the stratosphere additionally during 1-2 years after the eruption. Therafter the ozone layer recovers. In April 1993, after the eruption of Mt. Pinatubo (1991), the UV burden was still 40% higher than average. Miniholes and streamers can appear unexpected on a short-time scale and cross over Central Europe within 1-2 days, thus enhancing UV irradiation. The human skin reacts to UV exposure depending on the type of skin. The campaign "Sonne(n) mit Verstand" of the Bavarian Ministries for Environment, for Health and for Education informs about the danger of UV radiation (see www.sonne-mit-ver-stand.de). The German Weather Service informs the public on present developments of the ozone layer and relevant topics byits ozone bulletin, which is also available via internet under (www.dwd.de/deFundE/Observator/MOHp/hp2/ozon/bulletin.htm).

Climate↗

PubMed2003

[QUASA-the apheresis registry].

Quality saving measures are required at the execution of extracorporeal LDL apheresis therapy (LDL apheresis) by the NUB guidelines of the national committee of physicians and health insurance. The saving measures apply to specialist, organizational and apparatical conditions for execution and accounting of treatment methods. Furthermore, as a result of the lawful requirements of SGB V, complementary BUB guidelines were introduced in 1999. These ought to engage the therapeutic benefit of a LDL apheresis treatment. Beyond measures for quality assurance at execution a documentation of treatment is explicitly demanded. For two years now the non-profit Quasa gGmbH has been developed the quality assurance registry for LDL apheresis with the background of those requirements. Since March 2003 the apheresis physicians can voluntarily take part in the registry initiative by internet. Beside the clinical patient's medical history, treatment relevant data are recorded. Because of the analysis of the nationally ascertained clinical data, for the first time it will be possible for the medical profession to fulfill the guidelines of quality assurance for LDL apheresis. Moreover the treating apheresis physicians can establish an EDV-based individual patient documentation. All necessary measures of data protection and data security are in process on the technical and logistic realization of this registry initiative. An epidemiological data evaluation is regularly accomplished and the results are provided to the public.

Anticoagulants↗