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Biomedical subjects

S Ugomori

Publications and source records attributed to S Ugomori.

8 recordsLinked to original sources

Chest x-rays before ophthalmic surgery.

We retrospectively reviewed clinical records and preoperative chest x-ray films of 636 patients who had been admitted for ophthalmic surgery in 1990 and 1991. In our hospital, a preoperative chest roentgenogram routinely was examined for each patient. A total of 228 patients (35.8%) had an abnormal preoperative result. These abnormalities were more frequent in patients older than 40 years of age than in younger patients. Pulmonary fibrosis and calcification were the most common abnormal findings. Also, we noted that 202 patients (31.8%) had a chronic, previously known, or suspected, finding, and 26 patients (4.1%) had a new or unsuspected finding. The surgery was postponed or canceled in five patients (0.8%) because of the abnormal x-ray results.

Adolescent↗

Central retinal vein occlusion in two patients with immunoglobulin G multiple myeloma associated with blood hyperviscosity.

A 69-year-old man (Patient 1) complained of anorexia, lumbago, and seeing floaters OS. The results of laboratory tests showed immunoglobulin (Ig) G lambda-type multiple myeloma associated with blood hyperviscosity. Retinal hemorrhages OD and central retinal vein occlusion OS were found. A 71-year-old woman (Patient 2) with IgG kappa-type multiple myeloma had blood hyperviscosity. Retinal microaneurysms OD and central retinal vein occlusion OS were found. We believe that our patients represent rare cases of IgG multiple myeloma associated with blood hyperviscosity and central retinal vein occlusion.

Aged↗

Superficial punctate keratopathy and bacterial growth in patients with unilateral aphakia using extended-wear soft contact lenses.

We prospectively examined corneal conditions and bacterial growth in 77 individuals with unilateral aphakia who were using extended-wear soft contact lenses. The ratios of positive bacterial growth (70.6-79.4%) from 34 patients with superficial punctate keratopathy were significantly higher than those (41.9-46.5%) from the 43 subjects with normal corneas. Bacterial growth was found frequently in patients with superficial punctate keratopathy who were older than 80 years and in those using soft contact lenses for more than 22 days. Several kinds of bacteria grew from the specimens. Among the most common were Staphylococcus epidermidis and Corynebacterium species. Pseudomonas aeruginosa grew from patients with superficial punctate keratopathy who were using extended-wear soft contact lenses.

Aged↗

Optic nerve glioma in Japanese patients with neurofibromatosis 1. Case reports and literature review.

Case 1, a 6-year-old boy, had multiple café-au-lait spots, no light perception OS, Lisch nodules OU, pale optic disc OS, enlarged left optic nerve on computed tomographic scan and magnetic resonance imaging, and histopathologically verified pilocytic astrocytoma (glioma). The patient's mother had neurofibromatosis 1 (NF-1). Case 2, a 12-year-old boy, had multiple café-au-lait spots, decreased visual acuity OU, Lisch nodules OU, pale optic discs OU, enlarged optic nerves and chiasm on computed tomographic scan, and histopathologically verified pilocytic astrocytoma. We also examined 38 Japanese patients with NF-1 and found Lisch nodules in 95% and optic nerve glioma in 5%. After reviewing the recent literature, we found that the association of optic nerve glioma and NF-1 in the Japanese population was less than that reported in North America.

Adolescent↗

Polymorphonuclear leukocytes and bacterial growth of the normal and mildly inflamed conjunctiva.

We examined 304 conjunctiva in 152 subjects by clinical, cytologic, and bacteriologic methods. Bacteriologic samples were evaluated after a 48-hour incubation. Bacterial growth was found in 8 (20.5%) of 39 patients with clinically normal conjunctiva and no polymorphonuclear leukocytes (PMNs), and in 8 (61.5%) of 13 subjects with clinically normal conjunctiva and evidence of PMNs. Bacterial growth also was observed in 4 (40.0%) of 10 patients with clinically mild conjunctivitis and no PMNs, in 10 (24.4%) of 41 patients with clinically mild conjunctivitis and a mixture of inflammatory cells or predominantly lymphocytes, and in 37 (75.5%) of 49 patients with clinically mild conjunctivitis and evidence of PMNs. The presence of PMNs was well correlated with the existence of rapid-growing bacteria.

Adolescent↗

Pericentral retinal degeneration deteriorates during pregnancies.

A 25-year-old pregnant woman complained of a transient decrease of vision in her left eye. No ring scotoma was described. During her second pregnancy at age 27, the patient noticed subtle ring scotomas in both eyes. During her third pregnancy at age 30, the scotomas enlarged. A grayish zone with a few small areas of pigmentation around the macula was seen bilaterally. At age 37, the retinal degeneration progressed slightly: results of visual function and electrophysiologic examinations revealed mild rod and cone dysfunction. We believe that this patient represents a rare case of deteriorating pericentral retinal degeneration during pregnancies.

Adult↗

Abnormally distributed branches of the retinal vessels, enlarged macular arteries and long cilioretinal arteries.

We examined fundus photographs of 3,506 eyes and noted uncommon retinal vessel patterns in the temporal quadrants of the posterior fundus. Of 1,753 subjects, 20 patients (21 eyes) had unusual retinal vessel patterns. Seven eyes had an abnormally distributed branch of the inferotemporal artery; 8 eyes had an enlarged macular artery. Of these 20 patients, 1 had visual complaints associated with the unusual vascular patterns.

Adult↗

Combined hamartoma of the retina and retinal pigment epithelium of the juxtapapillary retina and optic disc.

An 11-year-old Japanese girl had a greenish-gray, slightly elevated lesion at the optic disc and juxtapapillary retina of the right eye that was diagnosed as a combined hamartoma of the retina and retinal pigment epithelium. A gliotic epiretinal membrane partially covered the lesion. Tortuous retinal vessels, which leaked fluorescein dye, were noted ophthalmoscopically. The lesion remained stable during a follow-up period of 1 year. After reviewing the Japanese literature, we concluded that the combined hamartoma may not be as rare in Japan as previously thought.

Child↗