Biomedical subjects

S V Pansare

Publications and source records attributed to S V Pansare.

3 recordsLinked to original sources

PubMed1986

Inhibition of L-lysine uptake by alpha-methyl lysine in Escherichia coli and Bacillus sphaericus.

alpha-Methyl lysine was investigated as a potential inhibitor of lysine transport in Escherichia coli and Bacillus sphaericus. At equimolar concentrations, no inhibition was observed in either organism, but at 10X and 100X the lysine concentration, alpha-methyl lysine caused a 20-50% reduction in the initial rate of lysine uptake in both bacteria. A similar inhibitory effect was observed with epsilon-N-methyl lysine on lysine uptake in B. sphaericus, but not in E. coli. alpha-Methyl lysine had a reduced effect on ornithine uptake and no effect on arginine transport in either bacterium.

Arginine↗

PubMed1984

Neuroblastoma in an adolescent.

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Adolescent↗

PubMedDate not supplied

Trityl isothiocyanate support for solid-phase synthesis.

Trityl isothiocyanate resin [1], prepared from commercially available trityl chloride resin, is a useful precursor of the trityl thiosemicarbazide resin [2]. This resin can be employed in the solid-phase synthesis of a variety of supported isatin beta-thiosemicarbazones [4] and their Mannich derivatives [6]. A variety of thioureas [7] can be easily prepared by the reaction of [1] with amines. The supported thioureas are directly and efficiently converted to 2-aminothiazole-5-carboxylates [8] by reaction with methyl 2-chloroacetoacetate.

Combinatorial Chemistry Techniques↗