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Biomedical subjects

S V Perepelkin

Publications and source records attributed to S V Perepelkin.

12 recordsLinked to original sources
PubMedDate not supplied

[Hygienic aspects of air pollution by sulfur-containing compounds].

The physiological and biochemical states of children and adults who resided in the vicinity of the sulphide-containing gas processing plant were studied. The chemical agents emitted by the plant were found to have adverse effects of the children's functional status, namely, decreased vital capacity of the lung, mental performance, retarded sensomotor responses, altered enzymatic system activity.

Adolescent↗
PubMedDate not supplied

[Hygienic assessment of physical and psychophysiologic development of children residing in the area of emissions of Orenburg gas-producing plants].

The children and adolescents residing in rural settlements located in the vicinity of sites of industrial extraction and processing of hydrogen sulphide-containing gas were studied. The drinking water and ambient air in these settlements were shown to be polluted. Low indices of the children's mental, physiological, and physical development were revealed.

Adolescent↗
PubMedDate not supplied

[Hygienic estimation of the levels of chemical substances in the soil of the Orengurg region].

Soil pollution has been comprehensively assessed in the agroindustrial region and its sources were defined. The results of ecological and hygienic assessment of natural and anthropogenic soil pollution suggest that there are increased concentrations of boron, chromium, nickel, and lead and deficient levels of iodine throughout the territory. There are higher levels of metal accumulation in the soil of the Eastern area. Soil pollution with lead, zinc, copper, tin, manganese, chromium, and nickel was higher in the urban area than in rural one, that with vanadium was higher in the rural area. The following 4 types of correlating associations of metals in the soil were identified: cobalt--nickel--chromium; copper--zinc; baron--zirconium; vanadium--manganese--boron.

Catchment Area, Health↗
PubMedDate not supplied

[Changes in the indices of lipid metabolism in patients with ischemic heart disease occupied in natural gas fields].

The influence of adaptation to periodic pressure-chamber hypoxia produced on the condition of the lipid spectrum of blood serum before and after adaptation as well as in 3, 6 and 10 months after hypoxic training was studied in 46 patients with ischemic heart disease working at a enterprise specializing in winning and processing the hydrogen-sulfide-containing gas-condensate. The adaptation therapy was found to result in a reliable reduction of the total cholesterol level, of the level of cholesterol of lipoproteins of the low and extra low densities and of triglycerides; it also contributed to the increase of cholesterol of lipoproteins of the high density in blood serum, which, in the end, ensures a reduced atherogenic coefficient. The positive-for-organism changes in the lipid spectrum of blood serum hold on in patients with coronary heart disease for as long as 6 months after the adaptation therapy. The nature and degree of blood lipids' changes depend on an initial level of the atherogenic index; they were maximally pronounced in persons with the index exceeding 3, and virtually absent in IHD patients with the atherogenicity coefficient being below the mentioned figure.

Cholesterol, HDL↗
PubMedDate not supplied

[The characteristics of the behavior and brain lipid peroxidation function of rats in acute inhalation exposure to a hydrogen sulfide-containing gas condensate].

As a result of the effect of the gas condensate containing hydrogen sulfide a depression takes place of orienting-investigatory activity of Wistar male rats in conditions of open field, disturbance of elaboration and reproduction of conditioned reflex of two-way avoidance, surplus accumulation in the cerebral cortex tissue of products of peroxide lipids oxidation and depression of catalase. The changes were of cyclic character and returned to the level of the control animals in 48 h after the finishing of the effect.

Administration, Inhalation↗
PubMedDate not supplied

[Content of trace elements in the bottoms of open water reservoirs in the Western part of the Orenburg Region].

The mean concentrations of trace elements were determined in the bottoms of open water reservoirs in the western part of the Orenburg Region. The content of chromium was found to exceed the maximum permissible concentration by about 5 times, that of zinc and nickel complies with the clarke; that of copper was nearly 2 times less than the clarke, that of cobalt and vanadium is nearly 1.5 times less. The concentrations of trace elements in the bottoms were compared with those in soil, portable water, and snow cover in order to elucidate possible sources of origin.

Chromium↗
PubMedDate not supplied

[Effects of hydrogen sulfide containing gas condensate on the hepatic microsomal monooxygenase system].

Chronic action of different xenobiotics which form a part of condensed hydrogen sulphide-containing gas causes substantial changes in the activity of xenobiotic metabolic enzymes, which is suggestive of the damaged hepatic microsomal monooxygenase system. As the rate of biotransformation becomes higher, there are increases in the activity of microsomal monooxygenases and in the generation of active oxygen forms and hydrogen peroxide, by impairing antiradical and antiperoxide mechanisms. The experimentally used concentration of substances as constituents of condensed gas corresponds to the maximum acceptable air concentration of in the working area of gas-refining plants, but the functional features of the body's detoxifying system--the hepatic monooxygenase system should be taken into account while developing preventive measures of occupational diseases.

Air Pollutants, Occupational↗