[Immunohematologic study in patients with erythremia].
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Biomedical subjects
Publications and source records attributed to S V Samuleva.
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Experiments on 40 male Wistar rats were made to study the effect of levamisole on the production of hemolysins in experimental hyperthyrosis. Levamisole (2.5 mg/kg bw) was administered once 1 day before immunization with sheep red blood cells. Levamisole was discovered to appreciably activate hemolysin production in the spleen of rats with experimental hyperthyrosis, which manifested a demonstrable inhibition of immune response. A possible mechanism of levamisole action is suggested.