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Biomedical subjects

S V Waikar

Publications and source records attributed to S V Waikar.

5 recordsLinked to original sources
PubMed1994

Inert placebo versus active medication. Patient blindability in clinical pharmacological trials.

Patient blindability was examined in clinical, psychopharmacological, double-blind, placebo-controlled trials involving medications for obsessive-compulsive disorder and major depression. Based on the presence of clinical improvement and side effects, patients were able to determine correctly whether they took medication versus placebo. On the basis of these preliminary findings, the authors question the blindability of patients in clinical trials. Implications for the continued use of double-blind, placebo-controlled trials are discussed.

Clinical Trials as Topic↗
PubMed1991

Self-derogations and the interpersonal theory.

The interpersonal theory of personality has been applied to explain depressed people's dilemma: The depressed person's submissive behavior invites dominating reactions from other people, and those reactions sustain the depressed person's depression. Experiments 1 and 2 showed that self-derogations connote submissiveness but are generally judged to be neutral in affiliation. Experiment 3 tested implications for the behavior of dysphoric and nondysphoric Ss as they interacted with a self-derogating, other-derogating, or nonderogating confederate partner. Ss selected a topic from a list and talked about it for 1 min: the confederate's script was fixed. The S's judgments of the confederate, choice of topics, satisfaction with the interaction, and actual responses were analyzed. Self-derogators were judged to be submissive, elicited dominating reactions, and selected more topics with negative content.

Adult↗
PubMedDate not supplied

Cognitive correlates of anxious and depressive symptomatology: an examination of the Helplessness/Hopelessness model.

Expectancies about future life events were assessed in anxious and depressed patients to test predictions of the Helplessness/Hopelessness model of anxiety and depression (Alloy, Kelly, Mineka, & Clements, 1990). In addition to expectancies for future events, patients from affective and anxiety treatment clinics completed anxiety and depression symptom ratings and positive and negative affects scales. Findings revealed partial support for the model. Negative outcome and helplessness expectancies were related specifically to depression. Cognitions regarding future positive events were interrelated and associated with symptom measures more strongly than were cognitions regarding negative events. Additionally, positive affects was more strongly related to depression than to anxiety symptom ratings. Implications and limitations of these findings are discussed.

Adult↗