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Biomedical subjects

S Várkonyi

Publications and source records attributed to S Várkonyi.

14 recordsLinked to original sources

Electron microscopic study of alcoholic liver disease with special attention to the changes of mesenchymal cells of the liver.

The authors investigated electron microscopically the biopsy material of 48 chronic alcoholic liver patients. On the basis of clinical and histological criteria 5 stages were differentiated: fatty liver, fatty liver with increased mesenchymal activity, acute alcoholic hepatitis, chronic alcoholic hepatitis, alcoholic cirrhosis. In each group changes of liver cell organelles and mesenchymal cells were compared. In this investigation it was demonstrated that liver cell damage--except for acute alcoholic hepatitis was not parallel with the severity of the clinical picture. On the contrary, the proliveration of mesenchymal cells, signs of its secretory activity and fibre forming, were in correlation with the progression of liver disease. The authors suggest that an intermediate stage must be taken into account between acute alcoholic hepatitis and alcoholic cirrhosis: the chronic progressive alcoholic hepatitis. It reminds morphologically to a great extent of the active chronic hepatitis and it is characterized not by severity of the injury of liver cell organelles, but by great proliferation of mesenchymal cells and lymphoid infiltration.

Adult↗

Serum beta1A/C-globulin level in early myocardial infarction.

Serial titration of the third component of complement (beta1A/C-globulin) was performed in 170 serum samples of 39 patients in the early period of acute myocardial infarction. During the first 24 hours there was a rise in mean concentration values. During the next 24 hours they remained unchanged, in severe cases the mean values even decreased. Subsequently the levels continued to increase. In 27 cases a sharp fall of the level exceeding the limit of normal changes was observed. It is suggested that during the early period of acute myocardial infarction the serum concentration of beta1A/C-globulin is under the influence of two opposite processes, one inducing a decrease, the other an increase of the level.

Complement C3↗

Intensive care in myocardial infarction: report on 840 cases.

On the basis of 840 cases of acute myocardial infarction an account is given on the activity of a coronary-care-unit organized in a regional hospital. The technical problems involved and the procedures applied are discussed. The complications of the early phase, in particular dysrhythmias, their prevention and treatment are dealt with in detail. While the mortality due to electric failure was significantly reduced by appropriate measures the mortality resulting from muscular insufficiency could not be improved by intensive care.

Anti-Arrhythmia Agents↗