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Biomedical subjects

S Vallance

Publications and source records attributed to S Vallance.

6 recordsLinked to original sources

Duodenectomy without pancreatectomy for extensive benign villous adenoma of the duodenum.

Villous adenomas of the duodenum are uncommon, but two have been treated recently in Blenheim. One of these was an extensive benign tumour involving most of the second part of the duodenum but causing no biliary tract obstruction. It was treated by pyloric sphincter-sparing duodenectomy without pancreatectomy, with repair by Roux loop to the bile and pancreatic ducts and proximal duodenum. This procedure does not appear to have been described previously.

Adenoma

Antiseptic vs. saline lavage in purulent and faecal peritonitis.

A prospective randomized trial compared antiseptic solutions and normal saline as a means of preventing morbidity and mortality from residual sepsis in patients with generalized peritonitis. Fifty-three patients, all given broad-spectrum antibiotics, were entered into the study. Twenty patients received a saline lavage, 19 lavage with chlorhexidine-gluconate and 14 a saline lavage with instillation of povidone-iodine. All deaths were due either to the severity of the presenting disease or co-existing complicating conditions. The incidence of postoperative pyrexia, wound infection and duration of hospital stay of the surviving patients were unaffected by lavage grouping.

Adolescent

Leucocyte ascorbic acid and the leucocyte count.

1. During the course of a nutritional survey on an Antarctic base, leucocyte ascorbic acid estimations (Denson & Bowers, 1961) were found to be significantly affected (P less than 0.0001) by the leucocyte count measured during analysis. 2. The effect was significantly less (P less than 0.05) when leucocyte levels were at or near saturation than when subsaturated. 3. This suggests that leucocytes share available ascorbic acid, especially in subsaturated subjects, and that assessment of nutritional status from the leucocyte ascorbic acid level should take account of the leucocyte count and the plasma ascorbic acid titre.

Adult