Biomedical subjects
Publications and source records attributed to S Vassileva.
Chronic mucocutaneous candidosis has been described in patients with impaired cell-mediated immunity. We describe a female patient with sarcoidosis who developed a Candida granuloma on her upper lip. Moderate impairment of the cell-mediated immunity was detected. Three months' treatment with ketoconazole was successful, but the lesion recurred at the same place after treatment was stopped.
The changes in the quantity, pH, protein and erythrocytes were studied in the gingival fluid of students with chronic catarrhal gingivitis and impaired oral hygiene due to dental-jaw deformities (DJD) after a 5-week hygienic-therapeutic course with the toothpaste "Propodent". The data about the indices studied in the experimental group--24 children and juveniles with DJD and chronica catarrhal gingivitis, aged from 8 to 16, were compared with the values of the indices studied in the control group of 10 children and juveniles without DJD and with clinically health periodontium of the same age. The comparison between the mean values of the quantity gingival fluid, pH, protein and erythrocytes of the experimental group, before and after the treatment, revealed: 78.6% reduction of the quantity of gingival fluid, 3.8% increase of pH, 93.74% reduction of protein and 95.98% reduction of erythrocytes. In this way, the indices studied in the experimental group after the treatment did not differ with statistical significance from those of the healthy children. The methods for determination of the quantity, pH, protein and erythrocytes, proposed by T. Dzemileva and P. Nenov, objectivized the clinically observed favourable changes in gingiva as a result from the hygienic-therapeutic course in the students with DJD and chronic catarrhal gingivitis.
A patient, employed in a plant nursery where cacti are grown, developed wide spread dyshidrotic dermatitis of the hands. This patient was histologically studied and cactus spines were found in several biopsied vesicles.
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Total protein, lactate and enzyme activity of alkaline and acid phosphatase and lactate dehydrogenase were determined in mixed non-stimulated saliva of healthy and periodontitis sick patients, aged from 15 to 17. Enzyme determination, expressed in U/l was performed with ready tests of Boehringer; total protein in g%--according to Netelsson, lactate--in mg/100 ml. Increased activity of alkaline phosphatase was observed, depending on the inflammatory processes of periodontium. With acid phosphatase the discrepancies were more negligible but with a marked tendency to increased enzyme activity. The changes in lactate quantity were also indicative. No statistically significant differences were established for lactate dehydrogenase and total protein. Conclusions have been drawn for the practice.