Saliva test as ovulation predictor.
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Adult↗
Biomedical subjects
S Veersema
Publications and source records attributed to S Veersema.
Triplet pregnancy after pulsatile gonadotrophin-releasing hormone treatment in an acromegalic woman.
A triplet pregnancy is reported in an acromegalic woman with hypothalamic amenorrhoea treated with pulsatile gonadotrophin-releasing hormone (GnRH). The patient was on bromocriptine medication and had slightly elevated growth hormone (GH) and somatomedin-C (Sm-C) levels. This probably accounted for the conception of triplets in the first stimulation cycle.
Acromegaly↗
Follicle stimulating hormone (FSH) dynamics of low dose step-up ovulation induction with FSH in patients with polycystic ovary syndrome.
Pharmacodynamics of follicle stimulating hormone (FSH) were studied during low dose step-up gonadotrophin therapy in patients with polycystic ovary syndrome (PCOS). To obtain stable levels of FSH, Metrodin was administered i.v. By making daily determinations, the FSH concentration was slowly increased in steps of approximately 1 IU/l. A total of 16 patients were treated for a maximum of three treatment cycles. Out of 38 treatment cycles, in 26 (68%) a single dominant follicle developed. The overall ovulation rate was 78%. FSH concentrations were evaluated with regard to intra- and interindividual variability of the FSH threshold and with regard to the relationship between FSH concentrations, FSH dose and treatment outcome. The high variability of the FSH threshold, ranging from 5.7 to 12 IU/l, appeared to be mainly a function of inter-individual variability. Higher FSH concentrations were associated with multifollicular growth as opposed to monofollicular growth, whereas the increases in concentration from a substimulating to a stimulating level were not. Multifollicular growth might thus be associated with a higher elevation of FSH concentration above the threshold. Different patterns of FSH concentration in the course of the growth phase of the dominant follicle in mono- compared to multifollicular cycles suggested a difference in the effect of endogenous FSH on the plasma concentration. Endogenous feedback on FSH release may therefore still play a role during treatment with exogenous FSH.
Adult↗
Pregnancy following transcervical transfer of oocyte and sperm.
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Cervix Uteri↗
Ambulatory transcervical resection of polyps with the Duckbill polyp snare: a modality for treatment of endometrial polyps.
We performed a retrospective analysis of cases in which polypectomy was performed with the Duckbill polyp snare and a prospective pain analysis in patients undergoing office-based hysteroscopy using a visual analog scale (VAS, range 0-10). The patients, both pre- and postmenopausal, underwent office hysteroscopy for abnormal uterine bleeding. In all, 116 cases of endometrial polyps were diagnosed and removed with the Duckbill polyp snare. This technique was easy to set up and allowed therapeutic hysteroscopy in a see-and-treat fashion during office hysteroscopy. In 188 patients, pain was evaluated using a VAS. Polypectomy with the Duckbill snare was well tolerated by patients, with a pain score of 4.8 compared with a pain score of 4.2 for diagnostic hysteroscopy. Therefore, we conclude that the Duckbill polyp snare is useful for operative office hysteroscopy and is well tolerated by patients.
Ambulatory Surgical Procedures↗