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Biomedical subjects

S Vyravanathan

Publications and source records attributed to S Vyravanathan.

6 recordsLinked to original sources

Hoarseness in tuberculosis.

A study has been made of hoarseness in 26 tuberculous patients in Kandy (Sri Lanka). Tuberculous inflammation of the vocal cord or ventricular fold was its cause in 18 of them, in 17 of whom the laryngeal infection was due to direct implantation of tubercle bacilli from lung cavities through cough; in one it was probably haematogenous. Hoarseness in the other eight patients was due to recurrent laryngeal nerve palsy, the nerve being involved in tuberculous lesions, in six instances in the mediastinum and in three instances in the right apical pleura. However caused, hoarseness associated with active inflammatory disease cleared with anti-tuberculous chemotherapy, whereas that associated with fibrosis persisted.

Adolescent↗

Guillain-Barré syndrome associated with tuberculosis.

Two cases of Guillain-Barré syndrome occurring in association with chronic pulmonary tuberculosis are reported. A cell-mediated, delayed hypersensitivity reaction to, or invasion of the nerve roots by tubercle bacilli would seem to be the likely explanation of the neuropathy.

Adolescent↗

Tuberculous peritonitis: a review of thirty-five cases.

The clinical course of 35 patients with tuberculous peritonitis notified in Kandy (Sri Lanka) over a 6-year period has been reviewed. The maximum incidence occurred in the age group 21 to 40 years and the female/male ratio was 3:2. Clinical features were non-specific and the main presenting features were fever (68.5%), abdominal pain (65.7%), abdominal distension (54.2%), abdominal mass (54.2%) and ascites (45.7%). The symptoms were of insidious onset and 85% had symptoms for more than one month. Chest X-ray revealed abnormality suggestive of tuberculosis in 47%. Intra-abdominal tuberculosis was suspected in 43% of 26 patients before laparotomy. Four of the 32 patients given anti-tuberculous drugs died. Overall mortality was 20%.

Adolescent↗

Tuberculosis presenting with hemiplegia.

Five cases are reported of tuberculous patients who presented with hemiplegia as the initial symptom of their illness. In three patients the paralysis improved rapidly and completely with institution of antituberculous treatment. One case which came to necropsy revealed that the cause of the hemiplegia was a tuberculoma situated in the internal capsule.

Adolescent↗