Biomedical subjects

S W Norton

Publications and source records attributed to S W Norton.

3 recordsLinked to original sources

PubMed1985

Corneal transplant infection by Paecilomyces lilacinus.

Paecilomyces lilacinus was cultured from an ulcerated corneal transplant, sections of which, following surgical removal, revealed dense mycelial growth throughout the corneal remnant and penetrating Descemet's membrane. PAS-stained sections showed, in addition to the hyphae, numerous small, ovoid elements consistent with conidia of P. lilacinus. Infection apparently had spread to the transplant from the recipient's cornea. The fungal isolate proved resistant, in vitro, to amphotericin B, 5-fluorocytosine, and pimaricin, but sensitive to ketoconazole and moderately sensitive to miconazole. Following a second transplant and intensive antifungal therapy, the infection appears to have been eliminated.

Aged↗

PubMed1980

Conjunctival bandage.

In those instances of corneal disease where a traditional hydrophilic bandage lens cannot be fitted, using the combination of a hydrophilic bandage lens and an overlying conjunctival flap is a relatively simple surgical procedure. It has the advantage of easy removability of the bandage lens while eliminating the possibility of accidental dislodgment of the bandage lens.

Adult↗

PubMedDate not supplied

Unilateral optic neuropathy following vincristine chemotherapy.

Two subjects with acute lymphatic leukemia have been observed to have unilateral optic neuropathy five to seven days following administration of Vincristine (2.0 mg/sq m) during maintenance chemotherapy. Both subjects were in mission at the time their ocular problems developed. After discontinuance of Vincristine therapy, marked vision improvement in the affected eye occurred over the ensuing months. It is presumed that Vincristine therapy was the cause of toxic optic neuropathy in these patients.

Antineoplastic Agents↗